Natural bacterial transformation involves the internalization and chromosomal integration of
DNA and has now been documented in∼ 80 species. Recent advances have established …

Quorum sensing (QS), a microbial cell-to-cell communication process, dynamically regulates
a variety of metabolism and physiological activities. In this review, we provide an update on …

Streptococcus pneumoniae becomes competent for genetic transformation when exposed to
an autoinducer peptide known as competence-stimulating peptide (CSP). This peptide was …

Intercellular chemical signaling in bacteria, commonly referred to as quorum sensing (QS),
relies on the production and detection of compounds known as pheromones to elicit …

Being the principal causative agent of bacterial pneumonia, otitis media, meningitis and
septicemia, the bacterium Streptococcus pneumoniae is a major global health problem. To …

Natural DNA transformation is a lateral gene transfer mechanism during which bacteria take
up naked DNA from their environment and stably integrate it in their genome. The proteins …

Streptococcus pneumoniae is a frequent colonizer of the human nasopharynx that has the
potential to cause severe infections such as pneumonia, bacteremia and meningitis. Despite …

Streptococcus pneumoniae (the pneumococcus) is an important human pathogen. Natural
genetic transformation, which was discovered in this species, involves internalization of …

Competence for genetic transformation allows the opportunistic human pathogen
Streptococcus pneumoniae to take up exogenous DNA for incorporation into its own …

Quorum sensing (QS) is a crucial regulatory mechanism controlling bacterial signalling and
holds promise for novel therapies against antimicrobial resistance. In Gram-positive …