The re-emergence of natural products for drug discovery in the genomics era
Natural products have been a rich source of compounds for drug discovery. However, their
use has diminished in the past two decades, in part because of technical barriers to …
use has diminished in the past two decades, in part because of technical barriers to …
Marine rare actinomycetes: a promising source of structurally diverse and unique novel natural products
Rare actinomycetes are prolific in the marine environment; however, knowledge about their
diversity, distribution and biochemistry is limited. Marine rare actinomycetes represent a …
diversity, distribution and biochemistry is limited. Marine rare actinomycetes represent a …
Marine natural products
Covering: 2014. Previous review: Nat. Prod. Rep., 2015, 32, 116–211 This review covers the
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …
Antiviral potential of green synthesized silver nanoparticles of Lampranthus coccineus and Malephora lutea
Background Viral and microbial infections constitute one of the most important life-
threatening problems. The emergence of new viral and bacterial infectious diseases …
threatening problems. The emergence of new viral and bacterial infectious diseases …
Dereplication strategies in natural product research: How many tools and methodologies behind the same concept?
The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …
the living beings chemistry. However, identification of drugable molecules within the …
Cheminformatics in natural product‐based drug discovery
This review seeks to provide a timely survey of the scope and limitations of cheminformatics
methods in natural product‐based drug discovery. Following an overview of data resources …
methods in natural product‐based drug discovery. Following an overview of data resources …
[HTML][HTML] Elicitation of secondary metabolism in actinomycetes
Genomic sequence data have revealed the presence of a large fraction of putatively silent
biosynthetic gene clusters in the genomes of actinomycetes that encode for secondary …
biosynthetic gene clusters in the genomes of actinomycetes that encode for secondary …
Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia
Trypanosomiasis is a protozoan disease transmitted via Trypanosoma brucei. This study
aimed to examine the metabolic profile and anti-trypanosomal effect of methanol extract of …
aimed to examine the metabolic profile and anti-trypanosomal effect of methanol extract of …
Bioprospecting sponge-associated microbes for antimicrobial compounds
Sponges are the most prolific marine organisms with respect to their arsenal of bioactive
compounds including antimicrobials. However, the majority of these substances are …
compounds including antimicrobials. However, the majority of these substances are …
Metabolomics analysis and biological investigation of three Malvaceae plants
Introduction Metabolomics is a fast growing technology that has effectively contributed to
many plant‐related sciences and drug discovery. Objective To use the non‐targeted …
many plant‐related sciences and drug discovery. Objective To use the non‐targeted …