Objectives The aim of this study is to provide updated guidance on when The Grading of
Recommendations Assessment, Development and Evaluation (GRADE) users should …

Clinical practices guidelines (CPGs) play a fundamental role in improving healthcare and
patients' outcomes by hel** clinicians make the best evidence-based decisions for their …

Bones comprise a significant percentage of human weight and have important physiologic
and structural roles. Bone remodeling occurs when healthy bone is renewed to maintain …

Treatment of bone defects remains a challenge in the clinic. Artificial bone grafts are the
most promising alternative to autologous bone grafting. However, one of the limiting factors …

Bone is one of the most highly adaptive tissues in the body, possessing the capability to alter
its morphology and function in response to stimuli in its surrounding environment. The ability …

Sports | Free Full-Text | Risk Factors, Diagnosis and Management of Bone Stress Injuries in
Adolescent Athletes: A Narrative Review Next Article in Journal Motor Performance in Male …

All Why? We recommend against the use of LIPUS Strong Benefits outweigh harms for
almost everyone. All or nearly all informed patients would likely want this option. Strong …

As explained by Wolff's law and the mechanostat hypothesis, mechanical stimulation can be
used to promote bone formation. Low intensity pulsed ultrasound (LIPUS) is a source of …