The antisaccade task is a measure of volitional control of behavior sensitive to fronto‐striatal
dysfunction. Here we outline important issues concerning antisaccade methodology …

In an effort to reveal susceptibility genes, schizophrenia research has turned to the
endophenotype strategy. Endophenotypes are characteristics that reflect the actions of …

Human eye movements are stereotyped and repeatable, but how specific to a normal
individual are the quantitative properties of his or her eye movements? We recorded …

Common mental disorders such as schizophrenia, bipolar disorder, and severe major
depression are highly heritable, but differ from single-gene (Mendelian) diseases in that they …

The idea that some phenotypes bear a closer relationship to the biological processes that
give rise to psychiatric illness than diagnostic categories has attracted considerable interest …

This study investigated the internal reliability, temporal stability and plasticity of commonly
used measures of inhibition-related functions. Stop-signal, go/no-go, antisaccade, Simon …

BACKGROUND: We have investigated which eye-movement tests alone and combined can
best discriminate schizophrenia cases from control subjects and their predictive validity …

The maintenance of a mental image in memory over a time scale of seconds is mediated by
the persistent discharges of neurons in a distributed brain network. The representation of the …

The search for liability genes of the world's 2 major psychotic disorders, schizophrenia and
bipolar disorder I (BP-I), has been extremely difficult even though evidence suggests that …

Eye tracking dysfunction (ETD) is one of the most widely replicated behavioral deficits in
schizophrenia and is over-represented in clinically unaffected first-degree relatives of …