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The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics
D Bautista-Sánchez, C Arriaga-Canon… - … therapy Nucleic acids, 2020 - cell.com
MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
expression via base-pairing complementarity. Their role in cancer can be related to tumor …
Functional interactions among microRNAs and long noncoding RNAs
In mammals, the vast majority of transcripts expressed are noncoding RNAs, ranging from
short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the …
short RNAs (including microRNAs) to long RNAs spanning up to hundreds of kb. While the …
[HTML][HTML] Ionizing radiation-induced epigenetic modifications and their relevance to radiation protection
M Belli, MA Tabocchini - International journal of molecular sciences, 2020 - mdpi.com
The present system of radiation protection assumes that exposure at low doses and/or low
dose-rates leads to health risks linearly related to the dose. They are evaluated by a …
dose-rates leads to health risks linearly related to the dose. They are evaluated by a …
Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer
Abstract Background Elevated microRNA-155 (miR-155) expression in non-small-cell lung
cancer (NSCLC) promotes cisplatin resistance and negatively impacts treatment outcomes …
cancer (NSCLC) promotes cisplatin resistance and negatively impacts treatment outcomes …
Understanding microRNA-mediated gene regulatory networks through mathematical modelling
The discovery of microRNAs (miRNAs) has added a new player to the regulation of gene
expression. With the increasing number of molecular species involved in gene regulatory …
expression. With the increasing number of molecular species involved in gene regulatory …
Circulating cell-free microRNAs as clinical cancer biomarkers
V Armand-Labit, A Pradines - Biomolecular concepts, 2017 - degruyter.com
MicroRNAs (miRNAs) are non-coding small RNAs that are master regulators of genic
expression and consequently of many cellular processes. But their expression is often …
expression and consequently of many cellular processes. But their expression is often …
Deciphering the role of miRNA in reprogramming plant responses to drought stress
Drought is the most prevalent environmental stress that affects plants' growth, development,
and crop productivity. However, plants have evolved adaptive mechanisms to respond to the …
and crop productivity. However, plants have evolved adaptive mechanisms to respond to the …
A state-of-the-art review on the MicroRNAs roles in hematopoietic stem cell aging and longevity
GGR Ortiz, Y Mohammadi, A Nazari… - Cell Communication and …, 2023 - Springer
Aging is a biological process determined through time-related cellular and functional
impairments, leading to a decreased standard of living for the organism. Recently, there has …
impairments, leading to a decreased standard of living for the organism. Recently, there has …
Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal …
Background The period of time when the embryo and the endometrium undergo significant
morphological alterations to facilitate a successful implantation—known as “window of …
morphological alterations to facilitate a successful implantation—known as “window of …
Interplay of microRNAs, transcription factors and target genes: linking dynamic expression changes to function
PV Nazarov, SE Reinsbach, A Muller… - Nucleic acids …, 2013 - academic.oup.com
MicroRNAs (miRNAs) are ubiquitously expressed small non-coding RNAs that, in most
cases, negatively regulate gene expression at the post-transcriptional level. miRNAs are …
cases, negatively regulate gene expression at the post-transcriptional level. miRNAs are …