The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

Trace amine-associated receptor 1 (TAAR1), the founding member of a nine-member family
of trace amine receptors, is responsible for recognizing a range of biogenic amines in the …

The present study investigated interactions between the novel psychoactive tryptamines
DiPT, 4-OH-DiPT, 4-OH-MET, 5-MeO-AMT, and 5-MeO-MiPT at monoamine receptors and …

The discovery in 2001 of a G protein-coupled receptor family, subsequently termed trace
amine-associated receptors (TAAR), triggered a resurgence of interest in so-called trace …

Trace amine-associated receptor 1 (TAAR1) has emerged as a promising therapeutic target
for neuropsychiatric disorders due to its ability to modulate monoaminergic and …

Methamphetamine (METH) is a powerful central nervous system stimulant which elevates
mood, alertness, energy levels and concentration in the short-term. However, chronic use …

TAAR1 is widely expressed across the mammalian brain, particularly in limbic and
monoaminergic areas, allegedly involved in mood, attention, memory, fear, and addiction …

Biogenic amines are a collection of endogenous molecules that play pivotal roles as
neurotransmitters and hormones. In addition to the “classical” biogenic amines resulting …

The extensive use of amphetamines to treat attention deficit hyperactivity disorders in
children provides a compelling rationale for understanding the mechanisms of action of …