Parahydrogen‐based hyperpolarization for biomedicine
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …
Hyperpolarized NMR Spectroscopy: d‐DNP, PHIP, and SABRE Techniques
The intensity of NMR signals can be enhanced by several orders of magnitude by using
various techniques for the hyperpolarization of different molecules. Such approaches can …
various techniques for the hyperpolarization of different molecules. Such approaches can …
Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research
A major challenge in cancer biology is to monitor and understand cancer metabolism in vivo
with the goal of improved diagnosis and perhaps therapy. Because of the complexity of …
with the goal of improved diagnosis and perhaps therapy. Because of the complexity of …
NMR hyperpolarization techniques for biomedicine
Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …
The theory and practice of hyperpolarization in magnetic resonance using parahydrogen
NMR spectroscopy is arguably the most powerful and versatile analytical spectroscopic
method available to analyze nuclides which possess a magnetic dipole moment and …
method available to analyze nuclides which possess a magnetic dipole moment and …
Iridium N-Heterocyclic Carbene Complexes as Efficient Catalysts for Magnetization Transfer from para-Hydrogen
While the characterization of materials by NMR is hugely important in the physical and
biological sciences, it also plays a vital role in medical imaging. This success is all the more …
biological sciences, it also plays a vital role in medical imaging. This success is all the more …
Instrumentation for hydrogenative parahydrogen-based hyperpolarization techniques
The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen,
parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a …
parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a …
ParaHydrogen Induced Polarization of 13C carboxylate resonance in acetate and pyruvate
The advent of nuclear spins hyperpolarization techniques represents a breakthrough in the
field of medical diagnoses by magnetic resonance imaging. Dynamic nuclear polarization …
field of medical diagnoses by magnetic resonance imaging. Dynamic nuclear polarization …
Applications of NMR spectroscopy to systems biochemistry
TWM Fan, AN Lane - Progress in nuclear magnetic resonance spectroscopy, 2016 - Elsevier
The past decades of advancements in NMR have made it a very powerful tool for metabolic
research. Despite its limitations in sensitivity relative to mass spectrometric techniques, NMR …
research. Despite its limitations in sensitivity relative to mass spectrometric techniques, NMR …
Hyperpolarising pyruvate through signal amplification by reversible exchange (SABRE)
Hyperpolarisation methods that premagnetise agents such as pyruvate are currently
receiving significant attention because they produce sensitivity gains that allow disease …
receiving significant attention because they produce sensitivity gains that allow disease …