The population of adults living with congenital heart disease (CHD) has grown rapidly in
recent decades due to major advances in surgical and medical care. Although the benefits …

Background: Despite developments in surgical techniques and medical care, people with a
Fontan circulation still experience long-term complications; non-invasive therapies to …

Fontan-type surgery is the final step in the sequential palliative surgical treatment of infants
born with a univentricular heart. The resulting long-term haemodynamic changes promote …

Background: People with a Fontan circulation usually have moderately impaired exercise
performance, although a subset have high physical performance (“Super-Fontan”), which …

The Fontan circulation describes the circulatory state resulting from an operation in
congenital heart disease where systemic venous return is directed to the lungs without an …

Surgical repair for children born with single-ventricle congenital heart disease, culminating
in the Fontan operation, has resulted in dramatic improvements in survival; children born …

Introduction Patients with a Fontan circulation are at risk for sequelae of Fontan physiology
during follow-up. Fontan physiology affects all organ systems and an overview of end-organ …

Background Lack of paediatric reference data limits the utility of handgrip strength as a
measure of fitness and well-being. Aim To develop paediatric handgrip reference curves …

The Fontan procedure is a common palliative surgery for congenital single ventricle patients.
In silico and in vitro patient-specific modeling approaches are widely utilized to investigate …

Despite traditional concerns about moderate-to-vigorous physical activity, current evidence
suggests that exercise is beneficial for the Fontan circulation and that, after appropriate …