Regulation of short-chain fatty acids in the immune system

XF Liu, JH Shao, YT Liao, LN Wang, Y Jia… - Frontiers in …, 2023 - frontiersin.org
A growing body of research suggests that short-chain fatty acids (SCFAs), metabolites
produced by intestinal symbiotic bacteria that ferment dietary fibers (DFs), play a crucial role …

Crosstalk between gut microbiota and host immunity: impact on inflammation and immunotherapy

C Campbell, MR Kandalgaonkar, RM Golonka… - Biomedicines, 2023 - mdpi.com
Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Gut microbial carbohydrate metabolism contributes to insulin resistance

T Takeuchi, T Kubota, Y Nakanishi, H Tsugawa… - Nature, 2023 - nature.com
Insulin resistance is the primary pathophysiology underlying metabolic syndrome and type 2
diabetes,. Previous metagenomic studies have described the characteristics of gut …

Metabolic adaptation of lymphocytes in immunity and disease

NM Chapman, H Chi - Immunity, 2022 - cell.com
Adaptive immune responses mediated by T cells and B cells are crucial for protective
immunity against pathogens and tumors. Differentiation and function of immune cells require …

Gut microbiota-derived short-chain fatty acids and colorectal cancer: Ready for clinical translation?

H Hou, D Chen, K Zhang, W Zhang, T Liu, S Wang… - Cancer Letters, 2022 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related death worldwide. It involves the complex interactions between genetic …

Colonization and development of the gut microbiome in calves

Y Du, Y Gao, M Hu, J Hou, L Yang, X Wang… - Journal of animal …, 2023 - Springer
Colonization and development of the gut microbiome are crucial for the growth and health of
calves. In this review, we summarized the colonization, beneficial nutrition, immune function …

Coprococcus eutactus, a Potent Probiotic, Alleviates Colitis via Acetate-Mediated IgA Response and Microbiota Restoration

R Yang, S Shan, J Shi, H Li, N An, S Li… - Journal of Agricultural …, 2023 - ACS Publications
Inflammatory bowel disease (IBD) is a complex disease characterized by relapsing episodes
of inflammation of the colonic mucosa. Research into IBD suggests that this disease …

Microbial metabolites and gut immunology

T Takeuchi, Y Nakanishi, H Ohno - Annual review of …, 2024 - annualreviews.org
The intestine is the largest peripheral lymphoid organ in animals, including humans, and
interacts with a vast array of microorganisms called the gut microbiota. Comprehending the …

Short chain fatty acid metabolism in relation to gut microbiota and genetic variability

G Ramos Meyers, H Samouda, T Bohn - Nutrients, 2022 - mdpi.com
It is widely accepted that the gut microbiota plays a significant role in modulating
inflammatory and immune responses of their host. In recent years, the host-microbiota …

Emerging role of gut microbiota in autoimmune diseases

X Wang, W Yuan, C Yang, Z Wang, J Zhang… - Frontiers in …, 2024 - frontiersin.org
Accumulating studies have indicated that the gut microbiota plays a pivotal role in the onset
of autoimmune diseases by engaging in complex interactions with the host. This review aims …