Protein analysis by shotgun/bottom-up proteomics

Y Zhang, BR Fonslow, B Shan, MC Baek… - Chemical …, 2013 - ACS Publications
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Isobaric labeling-based relative quantification in shotgun proteomics

N Rauniyar, JR Yates III - Journal of proteome research, 2014 - ACS Publications
Mass spectrometry plays a key role in relative quantitative comparisons of proteins in order
to understand their functional role in biological systems upon perturbation. In this review, we …

Quantitative proteomics using isobaric labeling: a practical guide

X Chen, Y Sun, T Zhang, L Shu… - Genomics …, 2021 - academic.oup.com
In the past decade, relative proteomic quantification using isobaric labeling technology has
developed into a key tool for comparing the expression of proteins in biological samples …

[HTML][HTML] Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes

JE Park, HS Tan, A Datta, RC Lai, H Zhang… - Molecular & cellular …, 2010 - Elsevier
Under hypoxia, tumor cells produce a secretion that modulates their microenvironment to
facilitate tumor angiogenesis and metastasis. Here, we observed that hypoxic or …

iTRAQ underestimation in simple and complex mixtures:“the good, the bad and the ugly”

SY Ow, M Salim, J Noirel, C Evans… - Journal of proteome …, 2009 - ACS Publications
The increasing popularity of iTRAQ for quantitative proteomics applications makes it
necessary to evaluate its relevance, accuracy, and precision for biological interpretation …

Molecular chemistry of organic aerosols through the application of high resolution mass spectrometry

SA Nizkorodov, J Laskin, A Laskin - Physical Chemistry Chemical …, 2011 - pubs.rsc.org
Understanding the molecular composition and fundamental chemical transformations of
organic aerosols (OA) during their formation and aging is both a major challenge and the …

High precision quantitative proteomics using iTRAQ on an LTQ Orbitrap: a new mass spectrometric method combining the benefits of all

T Köcher, P Pichler, M Schutzbier… - Journal of proteome …, 2009 - ACS Publications
The development of quantitative techniques in mass spectrometry has generated the ability
to systematically monitor protein expression. Isobaric tags for relative and absolute …

Creating a mass spectral reference library for oligosaccharides in human milk

CA Remoroza, TD Mak, MLA De Leoz… - Analytical …, 2018 - ACS Publications
We report the development and availability of a mass spectral reference library for
oligosaccharides in human milk. This represents a new variety of spectral library that …

Structural analysis of glycoprotein sialylation–part II: LC-MS based detection

G Palmisano, MR Larsen, NH Packer… - Rsc Advances, 2013 - pubs.rsc.org
Structural characterisation of sialylated glycoproteins in time and space is a requirement for
further understanding of their involvement in biology. In this second of two related reviews …

Proteomics and the search for welfare and stress biomarkers in animal production in the one-health context

A Marco-Ramell, AM de Almeida, S Cristobal… - Molecular …, 2016 - pubs.rsc.org
Stress and welfare are important factors in animal production in the context of growing
production optimization and scrutiny by the general public. In a context in which animal and …