Aging involves a diverse set of biological changes accumulating over time that leads to
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …

Aging as an irretrievable occurrence throughout the entire life is characterized by a
progressive decline in physiological functionality and enhanced disease vulnerability …

Behavioral and lifestyle factors have been shown to relate to a number of health-related
outcomes, yet there is a need for studies that examine their relationship to molecular aging …

Rationale: Epigenetic aging is a novel measure of biological age, reflecting exposures and
disease risks independent of chronological age. It may serve as a useful biomarker of …

Objective: Major depressive disorder is associated with an increased risk of mortality and
aging-related diseases. The authors examined whether major depression is associated with …

Background Cigarette smoke is a major public health concern. Epigenetic aging may be an
important pathway by which exposure to cigarette smoke affects health. However, little is …

Background Past research has linked low socio-economic status (SES) to inflammation,
metabolic dysregulation, and various chronic and age-related diseases such as type 2 …

DNA methylation (DNAm) algorithms of biological age provide a robust estimate of an
individual's chronological age and can predict their risk of age-related disease and mortality …

A growing body of evidence indicates that patients with cancer who receive cytotoxic
treatments (such as chemotherapy or radiotherapy) have an increased risk of accelerated …

Abstract GrimAge acceleration (GrimAgeAccel) and PhenoAge acceleration
(PhenoAgeAccel) are DNA methylation-based markers of accelerated biological aging …