Despite major achievements in child survival, the burden of neonatal mortality has remained
high and even increased in some countries since 1990. Currently, most neonatal deaths are …

The normal lung function trajectory from birth to death has three phases: a growth phase
(from birth to early adulthood), a plateau phase (that lasts for a few years), and a decline …

Airway remodeling is generally quite broadly defined as any change in composition,
distribution, thickness, mass or volume and/or number of structural components observed in …

Asthma is one of the most common diseases in the world, resulting in a substantial burden of
disease. Although rates of deaths due to asthma worldwide have reduced greatly over the …

Abstract Preterm birth (PTB) complicates 5–18% of pregnancies globally and is a leading
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …

Almost half of all preterm births are caused or triggered by an inflammatory process at the
feto-maternal interface resulting in preterm labor or rupture of membranes with or without …

Supplementation with members of the early-life microbiota as" probiotics" is increasingly
used in attempts to beneficially manipulate the preterm infant gut microbiota. We performed …

The recent Lancet commission has highlighted that “asthma” should be used to describe a
clinical syndrome of wheeze, breathlessness, chest tightness, and sometimes cough. The …

Early life is an important window of opportunity to improve health across the full lifecycle. An
accumulating body of evidence suggests that exposure to adverse stressors during early life …

The only text to cover lung function assessment from first principles including methodology,
reference values and interpretation New for this edition:-More illustrations to convey …