They react according to a succession of mono-or bimolecular processes to form at the end
one product that incorporates important portions and functionalities of the starting materials …

In the last two or three decades the emphasis on and applications of green chemical
principles, introduced some significant advances in organic synthesis, such as combinatorial …

Spirooxindoles are important synthetic targets possessing extended biological activity and
drug discovery applications. This review focuses on the various strategies for the …

Multicomponent reactions are flexible reactions for the rapid generation of complex
molecules with often biologically relevant scaffold structures. Combined with the ease of …

Spectroscopic analysis, DFT studies and surface enhanced Raman scattering (SERS) of
antimicrobial bioactive 4-[(5-tert-butyl) 2-hydroxybenzylidene] amino-N-(4, 6 …

A multicomponent reaction of 3-aminopyrazol-5-ones with substituted salicylic aldehydes
and acetylacetic ester leading to the formation of novel 2, 3-dihydrochromeno [4, 3-d] …

DNA Topoisomerases (Topos) are ubiquitous nuclear enzymes involved in regulating the
topological state of DNA and, in eukaryotic organisms, Topos can be classified into two …

Indane-1, 3-dione is a versatile building block used in numerous applications ranging from
biosensing, bioactivity, bioimaging to electronics or photopolymerization. In this review, an …

Because of the significant role in biological processes in living cells and the diverse types of
physiological activities, heterocyclic compounds are in focus of intense investigations by …

An economical, simple and efficient one-pot method has been developed for the synthesis of
thiazolo [3, 2-a] pyrimidine hydrobromide derivatives. 2, 4-diaryl-6, 7, 8, 9-tetrahydro-4 H …