Genetic mechanisms underlying feed utilization and implementation of genomic selection for improved feed efficiency in dairy cattle

LF Brito, HR Oliveira, K Houlahan… - Canadian journal of …, 2020 - cdnsciencepub.com
The economic importance of genetically improving feed efficiency has been recognized by
cattle producers worldwide. It has the potential to considerably reduce costs, minimize …

Genome-wide scanning for signatures of selection revealed the putative genomic regions and candidate genes controlling milk composition and coat color traits in …

SK Illa, S Mukherjee, S Nath, A Mukherjee - Frontiers in Genetics, 2021 - frontiersin.org
Background In the evolutionary time scale, selection shapes the genetic variation and alters
the architecture of genome in the organisms. Selection leaves detectable signatures at the …

Bovine milk-derived cells express transcriptome markers of pluripotency and secrete bioactive factors with regenerative and antimicrobial activity

N Danev, RM Harman, L Oliveira, L Huntimer… - Scientific Reports, 2023 - nature.com
The bovine mammary stem/progenitor cell secretome stimulates regeneration in vitro and
contains proteins associated with antimicrobial defense. This has led to the exploration of …

Assessment of imputation from low-pass sequencing to predict merit of beef steers

WM Snelling, JL Hoff, JH Li, LA Kuehn, BN Keel… - Genes, 2020 - mdpi.com
Decreasing costs are making low coverage sequencing with imputation to a comprehensive
reference panel an attractive alternative to obtain functional variant genotypes that can …

The mammosphere-derived epithelial cell secretome modulates neutrophil functions in the bovine model

RM Harman, A Sipka, KA Oxford, L Oliveira… - Frontiers in …, 2024 - frontiersin.org
Background Innovative therapies against bacterial infections are needed. One approach is
to focus on host-directed immunotherapy (HDT), with treatments that exploit natural …

A multi-breed reference panel and additional rare variants maximize imputation accuracy in cattle

TN Rowan, JL Hoff, TE Crum, JF Taylor… - Genetics Selection …, 2019 - Springer
Background During the last decade, the use of common-variant array-based single
nucleotide polymorphism (SNP) genoty** in the beef and dairy industries has produced …

Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertility

M Hiltpold, G Niu, NK Kadri, D Crysnanto, ZH Fang… - PLoS …, 2020 - journals.plos.org
Cattle are ideally suited to investigate the genetics of male reproduction, because semen
quality and fertility are recorded for all ejaculates of artificial insemination bulls. We analysed …

Genotype imputation as a cost-saving genomic strategy for South African Sanga cattle: A review

SF Lashmar, FC Muchadeyi, C Visser - South African Journal of Animal …, 2019 - ajol.info
Abstract The South African beef cattle population is heterogeneous and consists of a variety
of breeds, production systems and breeding goals. Indigenous cattle breeds are uniquely …

[HTML][HTML] Genome-wide association study between copy number variants and hoof health traits in Holstein dairy cattle

AM Butty, TCS Chud, DF Cardoso, LSF Lopes… - Journal of dairy …, 2021 - Elsevier
Genome-wide association studies based on SNP have been completed for multiple traits in
dairy cattle; however, copy number variants (CNV) could add genomic information that has …

Genome-wide association analyses identify genotype-by-environment interactions of growth traits in Simmental cattle

CU Braz, TN Rowan, RD Schnabel, JE Decker - Scientific reports, 2021 - nature.com
Understanding genotype-by-environment interactions (G× E) is crucial to understand
environmental adaptation in mammals and improve the sustainability of agricultural …