The essential medicinal chemistry of curcumin: miniperspective

KM Nelson, JL Dahlin, J Bisson, J Graham… - Journal of medicinal …, 2017 - ACS Publications
Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

AS Azmi, B Bao, FH Sarkar - Cancer and Metastasis Reviews, 2013 - Springer
Trafficking of biological material across membranes is an evolutionary conserved
mechanism and is part of any normal cell homeostasis. Such transport is composed of …

Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study

A Haroyan, V Mukuchyan, N Mkrtchyan… - … and alternative medicine, 2018 - Springer
Background The aim of this clinical trial was to assess the efficacy and safety of curcuminoid
complex extract from turmeric rhizome with turmeric volatile oil (CuraMed®) and its …

Current status and progress of pancreatic cancer in China

QJ Lin, F Yang, C **, DL Fu - World Journal of …, 2015 - pmc.ncbi.nlm.nih.gov
Cancer is currently one of the most important public health problems in the world. Pancreatic
cancer is a fatal disease with poor prognosis. As in most other countries, the health burden …

Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet

DC Willcox, G Scapagnini, BJ Willcox - Mechanisms of ageing and …, 2014 - Elsevier
The traditional diet in Okinawa is anchored by root vegetables (principally sweet potatoes),
green and yellow vegetables, soybean-based foods, and medicinal plants. Marine foods …

Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects

M Purpura, RP Lowery, JM Wilson, H Mannan… - European journal of …, 2018 - Springer
Purpose The optimal health benefits of curcumin are limited by its low solubility in water and
corresponding poor intestinal absorption. Cyclodextrins (CD) can form inclusion complexes …

Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse model

Z Zhang, DJ Leong, L Xu, Z He, A Wang… - Arthritis research & …, 2016 - Springer
Background Curcumin has been shown to have chondroprotective potential in vitro.
However, its effect on disease and symptom modification in osteoarthritis (OA) is largely …

[HTML][HTML] Cancer metabolism as a therapeutic target and review of interventions

MTJ Halma, JA Tuszynski, PE Marik - Nutrients, 2023 - mdpi.com
Cancer is amenable to low-cost treatments, given that it has a significant metabolic
component, which can be affected through diet and lifestyle change at minimal cost. The …

[HTML][HTML] Turmeric and curcumin—health-promoting properties in humans versus dogs

J Kępińska-Pacelik, W Biel - International Journal of Molecular Sciences, 2023 - mdpi.com
The growing popularity of the use of nutraceuticals in the prevention and alleviation of
symptoms of many diseases in humans and dogs means that they are increasingly the …

Targeting cancer stem cells by curcumin and clinical applications

Y Li, T Zhang - Cancer letters, 2014 - Elsevier
Curcumin is a well-known dietary polyphenol derived from the rhizomes of turmeric, an
Indian spice. The anticancer effect of curcumin has been demonstrated in many cell and …