The increasing threat of Pseudomonas aeruginosa high-risk clones

A Oliver, X Mulet, C López-Causapé, C Juan - Drug Resistance Updates, 2015 - Elsevier
The increasing prevalence of chronic and hospital-acquired infections produced by
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …

Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis

MD Parkins, R Somayaji, VJ Waters - Clinical microbiology …, 2018 - journals.asm.org
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …

Clinical significance and pathogenesis of staphylococcal small colony variants in persistent infections

BC Kahl, K Becker, B Löffler - Clinical microbiology reviews, 2016 - journals.asm.org
Small colony variants (SCVs) were first described more than 100 years ago for
Staphylococcus aureus and various coagulase-negative staphylococci. Two decades ago …

Activity of Bacteriophages in Removing Biofilms of Pseudomonas aeruginosa Isolates from Chronic Rhinosinusitis Patients

SA Fong, A Drilling, S Morales, ME Cornet… - Frontiers in cellular …, 2017 - frontiersin.org
Introduction: Pseudomonas aeruginosa infections are prevalent amongst chronic
rhinosinusitis (CRS) sufferers. Many P. aeruginosa strains form biofilms, leading to treatment …

Pseudomonas aeruginosa infection in cystic fibrosis: pathophysiological mechanisms and therapeutic approaches

H Lund-Palau, AR Turnbull, A Bush… - Expert review of …, 2016 - Taylor & Francis
Pseudomonas aeruginosa is a remarkably versatile environmental bacterium with an
extraordinary capacity to infect the cystic fibrosis (CF) lung. Infection with P. aeruginosa …

Map** the Tail Fiber as the Receptor Binding Protein Responsible for Differential Host Specificity of Pseudomonas aeruginosa Bacteriophages PaP1 and JG004

S Le, X He, Y Tan, G Huang, L Zhang, R Lux, W Shi… - PloS one, 2013 - journals.plos.org
The first step in bacteriophage infection is recognition and binding to the host receptor,
which is mediated by the phage receptor binding protein (RBP). Different RBPs can lead to …

Antimicrobial resistance and virulence of Pseudomonas spp. among healthy animals: concern about exolysin ExlA detection

L Ruiz-Roldán, B Rojo-Bezares, M de Toro, M López… - Scientific reports, 2020 - nature.com
Pseudomonas is a ubiquitous genus that also causes human, animal and plant diseases.
Most studies have focused on clinical P. aeruginosa strains from humans, but they are …

Microevolution of Pseudomonas aeruginosa in the airways of people with cystic fibrosis

N Cramer, J Klockgether, B Tümmler - Current Opinion in Immunology, 2023 - Elsevier
Highlights•Pseudomonas aeruginosa in CF airways: paradigm of bacterial microevolution.•
Evolution within CF host triggers conversions of genotype and phenotype.•Severity of lung …

Pseudomonas aeruginosa infection in cystic fibrosis lung disease and new perspectives of treatment: a review

MC Gaspar, W Couet, JC Olivier, A Pais… - European Journal of …, 2013 - Springer
Cystic fibrosis (CF) is a complex inherited disease which affects many organs, including the
pancreas and liver, gastrointestinal tract and reproductive system, sweat glands and …

Develo** an international Pseudomonas aeruginosa reference panel

A De Soyza, AJ Hall, E Mahenthiralingam… - …, 2013 - Wiley Online Library
Pseudomonas aeruginosa is a major opportunistic pathogen in cystic fibrosis (CF) patients
and causes a wide range of infections among other susceptible populations. Its inherent …