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Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …
Conquering the hypoxia limitation for photodynamic therapy
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy
B Ji, M Wei, B Yang - Theranostics, 2022 - pmc.ncbi.nlm.nih.gov
Cancer immunotherapy has made tremendous clinical progress in advanced-stage
malignancies. However, patients with various tumors exhibit a low response rate to …
malignancies. However, patients with various tumors exhibit a low response rate to …
Engineering nanomedicine for glutathione depletion-augmented cancer therapy
Y **ong, C **ao, Z Li, X Yang - Chemical Society Reviews, 2021 - pubs.rsc.org
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
[HTML][HTML] Photodynamic therapy combined with immunotherapy: Recent advances and future research directions
M Warszyńska, P Repetowski, JM Dąbrowski - Coordination Chemistry …, 2023 - Elsevier
Innovative anticancer therapies based on the activation of the immune system offer promise
in the battle against cancers resistant to traditional treatments. Examples of such therapeutic …
in the battle against cancers resistant to traditional treatments. Examples of such therapeutic …
Emerging photodynamic nanotherapeutics for inducing immunogenic cell death and potentiating cancer immunotherapy
S Zhang, J Wang, Z Kong, X Sun, Z He, B Sun, C Luo… - Biomaterials, 2022 - Elsevier
Immunotherapy has emerged as a promising cancer treatment modality. Despite the rapid
progress in cancer immunotherapy, the therapeutic efficiency and clinical translation of …
progress in cancer immunotherapy, the therapeutic efficiency and clinical translation of …
Targeting immunogenic cancer cell death by photodynamic therapy: past, present and future
R Alzeibak, TA Mishchenko… - Journal for …, 2021 - pmc.ncbi.nlm.nih.gov
The past decade has witnessed major breakthroughs in cancer immunotherapy. This
development has been largely motivated by cancer cell evasion of immunological control …
development has been largely motivated by cancer cell evasion of immunological control …
A carbonic anhydrase IX (CAIX)‐anchored rhenium (I) photosensitizer evokes pyroptosis for enhanced anti‐tumor immunity
X Su, WJ Wang, Q Cao, H Zhang, B Liu… - Angewandte Chemie …, 2022 - Wiley Online Library
An ideal cancer treatment should not only destroy primary tumors but also improve the
immunogenicity of the tumor microenvironment to achieve a satisfactory anti‐tumor immune …
immunogenicity of the tumor microenvironment to achieve a satisfactory anti‐tumor immune …
Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges
Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …
survival have been modest and, in some examples, less than those of other approved …
Renal clearable ultrasmall single-crystal Fe nanoparticles for highly selective and effective ferroptosis therapy and immunotherapy
H Liang, X Wu, G Zhao, K Feng, K Ni… - Journal of the American …, 2021 - ACS Publications
Iron-based nanoparticles have attracted much attention because of their ability to induce
ferroptosis via a catalyzing Fenton reaction and to further potentiate immunotherapy …
ferroptosis via a catalyzing Fenton reaction and to further potentiate immunotherapy …