Our ability to detect, image, and quantify nanoscopic objects and molecules with visible light
has undergone dramatic improvements over the past few decades. While fluorescence has …

Label-free microscope imaging techniques allow direct visualization of biological
substances in their most native forms. This review article provides an overview of recent …

Interferometric scattering microscopy is increasingly employed in biomedical research owing
to its extraordinary capability of detecting nano-objects individually through their intrinsic …

Nanoparticles have been used extensively in biology-related research and many
applications require direct visualization of individual nanoparticles by optical microscopy …

We report that flat substrates such as glass coverslips with surface roughness well below 0.5
nm feature notable speckle patterns when observed with high-sensitivity interference …

Non-invasive characterization of powders may take one of two approaches: imaging and
counting individual particles; or relying on scattered light to estimate the particle size …

Mid-infrared photothermal (MIP) microscopy has been a promising label-free chemical
imaging technique for functional characterization of specimens owing to its enhanced spatial …

Interferometric scattering (iSCAT) microscopy is a powerful tool for label-free sensitive
detection and imaging of nanoparticles to high spatiotemporal resolution. As it was born out …

Label-free, visible light microscopy is an indispensable tool for studying biological
nanoparticles (BNPs). However, conventional imaging techniques have two major …

The sensitive detection and quantitative measurement of biological nanoparticles such as
viruses or exosomes is of growing importance in biology and medicine since these …