Purpose To systematically review the clinical features, management, and outcomes of
diffuse midline H3K27-altered gliomas of the spinal cord (DMG-SCs). Methods PubMed …

Intramedullary astrocytomas represent approximately 30%–40% of all intramedullary tumors
and are the most common intramedullary tumor in children. Surgical resection is considered …

Background Determining the grade and molecular marker status of intramedullary gliomas is
important for assessing treatment outcomes and prognosis. Invasive biopsy for pathology …

Intramedullary astrocytomas (IMAs) are rare tumors, and few studies specific to the
molecular alterations of IMAs have been performed. Recently, KIAA1549-BRAF fusions and …

Background Spinal cord glioma (SCG) is considered an orphan disease that lacks effective
treatment options with margins that are surgically inaccessible and an overall paucity of …

In this review, a stem cell concept, initially defined by the author more than 10 years ago
focusing on neural stem cells, has been systematically refined and updated. Relative to the …

The prevalence of spinal tumors is rare in comparison to brain tumors which encompass
most central nervous system tumors. Tumors of the spine can be divided into primary and …

This invited concise review was written for the special issue of Cell Transplantation to
celebrate the 25th anniversary of the American Society for Neural Therapy and Repair …

Intramedullary spinal cord glioblastoma (ISCG) is lethal due to lack of effective treatment. We
previously established a rat C6-ISCG model and the antitumor effect of F3. CD-TK, an hNSC …

Simple Summary Spinal cord tumors encompass a diverse range of rare neoplasms
originating from tissues in and around the spinal canal. Traditional treatment modalities like …