PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

P Grossen, D Witzigmann, S Sieber… - Journal of Controlled …, 2017 - Elsevier
The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

Biodegradable diblock copolymeric PEG-PCL nanoparticles: Synthesis, characterization and applications as anticancer drug delivery agents

A Behl, VS Parmar, S Malhotra, AK Chhillar - Polymer, 2020 - Elsevier
Poly (ethylene glycol) methyl ether-block-poly (Ɛ-caprolactone) copolymers are useful
biomedical materials owing to their amphiphilic nature, biodegradability, biocompatibility …

Gold nanorods coated with mesoporous silica shell as drug delivery system for remote near infrared light‐activated release and potential phototherapy

J Liu, C Detrembleur, MC De Pauw‐Gillet, S Mornet… - Small, 2015 - Wiley Online Library
In this study, we report the synthesis of a nanoscaled drug delivery system, which is
composed of a gold nanorod‐like core and a mesoporous silica shell (GNR@ MSNP) and …

Chiral nanomaterials for tumor therapy: autophagy, apoptosis, and photothermal ablation

Z Peng, L Yuan, J XuHong, H Tian, Y Zhang… - Journal of …, 2021 - Springer
Chirality is a fundamental characteristic of natural molecules and a crucial factor in the
biochemical reactions of living cells and organisms. Recently, researchers have successfully …

Poly(N‐vinylcaprolactam): A Thermoresponsive Macromolecule with Promising Future in Biomedical Field

J Liu, A Debuigne, C Detrembleur… - Advanced healthcare …, 2014 - Wiley Online Library
Poly (N‐vinylcaprolactam)(PNVCL) is a thermoresponsive and biocompatible polymer that
raises an increasing interest in the biomedical area, especially in drug delivery systems …

Current status and future perspectives of gold nanoparticle vectors for siRNA delivery

Á Artiga, I Serrano-Sevilla, L De Matteis… - Journal of Materials …, 2019 - pubs.rsc.org
Discovering the vast therapeutic potential of siRNA opened up new clinical research areas
focussing on a number of diseases and applications; however significant problems with …

Design of hybrid nanovehicles for remotely triggered drug release: an overview

J Liu, C Detrembleur, S Mornet, C Jérôme… - Journal of materials …, 2015 - pubs.rsc.org
In the past few decades, various nanovehicles have been developed as drug delivery
systems, in which inorganic and organic components are integrated within a nano-object …

Spatio-temporal control strategy of drug delivery systems based nano structures

N Rahoui, B Jiang, N Taloub, YD Huang - Journal of Controlled Release, 2017 - Elsevier
The drug instability, toxicity and the barrier to the target area necessitate a suitable drug
delivery system with an external or internal control of the release. Spatio-temporal control …

Automatically modulated thermoresponsive film based on a phase-changing copolymer

Y Liu, J Fan, R Plamthottam, M Gao, Z Peng… - Chemistry of …, 2021 - ACS Publications
Thermoresponsive materials, in particular those exhibiting switchable optical transmittance
via temperature change, have been widely used in different applications. If the required …

Chiral polymer modified nanoparticles selectively induce autophagy of cancer cells for tumor ablation

L Yuan, F Zhang, X Qi, Y Yang, C Yan, J Jiang… - Journal of …, 2018 - Springer
Background Autophagy regulation through exogenous materials has aroused intensive
attention to develop treatment protocols according to diverse human diseases. However, to …