Gliomas are the most common primary intracranial tumor, representing 81% of malignant
brain tumors. Although relatively rare, they cause significant mortality and morbidity …

The WHO 2007 glioma classification system (based primarily on tumour histology) resulted
in considerable interobserver variability and substantial variation in patient survival within …

Background The prediction of clinical behavior, response to therapy, and outcome of
infiltrative glioma is challenging. On the basis of previous studies of tumor biology, we …

Gliomas are primary brain tumours that are thought to derive from neuroglial stem or
progenitor cells. On the basis of their histological appearance, they have been traditionally …

Background CBTRUS is currently the only population-based site-specific registry in the US
that works in partnership with a public cancer surveillance organization, the CDC's NPCR …

Genome-wide association studies (GWAS) provide an agnostic approach for investigating
the genetic basis of complex diseases. In oncology, GWAS of nearly all common …

Primary brain tumors account for~ 1% of new cancer cases and~ 2% of cancer deaths in the
United States; however, they are the most commonly occurring solid tumors in children …

Brain and central nervous system (CNS) tumors represent approximately 1% of all newly
diagnosed cancers in the United States, and about 2% of cancer deaths. 1, 2 These are a …

Genome-wide association studies have identified more than 70 common variants that are
associated with breast cancer risk. Most of these variants map to non-protein-coding regions …

Establishing causal links between inherited polymorphisms and cancer risk is challenging.
Here, we focus on the single-nucleotide polymorphism rs55705857, which confers a sixfold …