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Advances in rapid point-of-care virus testing
Outbreaks of viral diseases seriously jeopardize people's health and cause huge economic
losses. At the same time, virology provides a new perspective for biology, molecular biology …
losses. At the same time, virology provides a new perspective for biology, molecular biology …
[HTML][HTML] The enigmatic epitranscriptome of bacteriophages: putative RNA modifications in viral infections
Highlights•RNA can be modified by diverse internal and terminal modifications.•Bacteria and
bacteriophage RNA polymerases can install RNA modifications.•Bacterial enzymes remove …
bacteriophage RNA polymerases can install RNA modifications.•Bacterial enzymes remove …
[HTML][HTML] The RNA revolution in the central molecular biology dogma evolution
WA Haseltine, R Patarca - International Journal of Molecular Sciences, 2024 - mdpi.com
Human genome projects in the 1990s identified about 20,000 protein-coding sequences.
We are now in the RNA revolution, propelled by the realization that genes determine …
We are now in the RNA revolution, propelled by the realization that genes determine …
Characterization of the symmetrical benzimidazole twin drug TL1228: the role as viral entry inhibitor for fighting COVID-19
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is reliably one of the
largest pandemics the world has suffered in recent years. In the search for non-biological …
largest pandemics the world has suffered in recent years. In the search for non-biological …
Analysis of the abundance and diversity of RNA secondary structure elements in RNA viruses using the RNAsselem Python package
FM Kazanov, EV Matveev, GV Ponomarev… - Scientific Reports, 2024 - nature.com
Recent advancements in experimental and computational methods for RNA secondary
structure detection have revealed the crucial role of RNA structural elements in diverse …
structure detection have revealed the crucial role of RNA structural elements in diverse …
[HTML][HTML] Reovirus infection induces transcriptome-wide unique A-to-I editing changes in the murine fibroblasts.
The conversion of Adenosine (A) to Inosine (I), by Adenosine Deaminases Acting on RNA or
ADARs, is an essential post-transcriptional modification that contributes to proteome …
ADARs, is an essential post-transcriptional modification that contributes to proteome …
RNA editing in host lncRNAs as potential modulator in SARS-CoV-2 variants-host immune response dynamics
Both host and viral RNA editing plays a crucial role in host's response to infection, yet our
understanding of host RNA editing remains limited. In this study of in-house generated RNA …
understanding of host RNA editing remains limited. In this study of in-house generated RNA …
[HTML][HTML] Genomic Landscape and Regulation of RNA Editing in Pekin Ducks Susceptible to Duck Hepatitis A Virus Genotype 3 Infection
H Zhao, Z Wu, Z Wang, J Ru, S Wang, Y Li… - International Journal of …, 2024 - mdpi.com
RNA editing is increasingly recognized as a post-transcriptional modification that directly
affects viral infection by regulating RNA stability and recoding proteins. the duck hepatitis A …
affects viral infection by regulating RNA stability and recoding proteins. the duck hepatitis A …
BEND6 promotes RNA viruses' replication by inhibiting innate immune responses
T Chen, L Ding, S Tu, H Sun, J Zou, A Ouyang… - Science China Life …, 2025 - Springer
Innate immunity serves as a crucial defense mechanism against invading pathogens, yet its
negative regulatory network remains under explored. In this study, we identify BEN domain …
negative regulatory network remains under explored. In this study, we identify BEN domain …
New Protein Variants Resulting from RNA Editing May Lead to Proteotoxic Stress
S Ben-Aroya, A Avram-Shperling, A Ben-David… - 2023 - researchsquare.com
Maintaining protein homeostasis is critical for cellular function, as disruptions can result in
accumulation of misfolded proteins associated with various diseases. RNA editing …
accumulation of misfolded proteins associated with various diseases. RNA editing …