Pharmacological significance of nitrogen-containing five and six-membered heterocyclic scaffolds as potent cholinesterase inhibitors for drug discovery
N-heterocycles are crucial due to their biological, chemical, and practical significance. They
are heavily investigated in biological processes involving anticancer, anti-inflammatory …
are heavily investigated in biological processes involving anticancer, anti-inflammatory …
[HTML][HTML] Photocatalytic degradation of Rhodamine B (RhB) dye in waste water and enzymatic inhibition study using cauliflower shaped ZnO nanoparticles synthesized …
Abstract The ZnO nanoparticles (NPs) are considered to be one of the inexpensive and very
important bioactive materials widely used in drug delivery, as a photo-catalyst material …
important bioactive materials widely used in drug delivery, as a photo-catalyst material …
[HTML][HTML] Synthesis and inhibition profiles of N-benzyl-and N-allyl aniline derivatives against carbonic anhydrase and acetylcholinesterase–A molecular docking study
The alkyl and aryl derivatives of aniline are important starting materials in fine organic
synthesis. Allyl bromide and benzyl chloride were taken as substrates for the alkylation …
synthesis. Allyl bromide and benzyl chloride were taken as substrates for the alkylation …
Comprehensive Metabolite Profiling of Cinnamon (Cinnamomum zeylanicum) Leaf Oil Using LC-HR/MS, GC/MS, and GC-FID: Determination of Antiglaucoma …
In this study, for the first time, the antioxidant and antidiabetic properties of the essential oil
from cinnamon (Cinnamomum zeylanicum) leaves were evaluated and investigated using …
from cinnamon (Cinnamomum zeylanicum) leaves were evaluated and investigated using …
Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo [2, 1-b][1, 3, 4] thiadiazoles as highly potent acetylcholinesterase and non …
Imidazole and thiadiazole derivatives display an extensive application in pharmaceutical
chemistry, and they have been investigated as bioactive molecules for medicinal chemistry …
chemistry, and they have been investigated as bioactive molecules for medicinal chemistry …
Isofraxidin: Antioxidant, Anti‐carbonic Anhydrase, Anti‐cholinesterase, Anti‐diabetic, and in Silico Properties
The development of innovative pharmacological formulations for the treatment and
prevention of various major diseases, including cancer, diabetes, and glaucoma, has been …
prevention of various major diseases, including cancer, diabetes, and glaucoma, has been …
[HTML][HTML] Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS
Many chronic diseases such as diabetes and Alzheimer's disease are related to the type
and quality of foods, which are consumed. Particularly, various plant origin products are …
and quality of foods, which are consumed. Particularly, various plant origin products are …
Molecular docking and inhibition studies of vulpinic, carnosic and usnic acids on polyol pathway enzymes
Aldose reductase (AR) and sorbitol dehydrogenase (SDH) are important enzymes of the
polyol pathway. In the current study, inhibitory effects of vulpinic acid (VA) carnosic acid (CA) …
polyol pathway. In the current study, inhibitory effects of vulpinic acid (VA) carnosic acid (CA) …
Thiosemicarbazides, 1, 3, 4 thiadiazole Schiff base derivatives of transition metal complexes as antimicrobial agents
M Pervaiz, R Quratulain, A Ejaz, M Shahin… - Inorganic Chemistry …, 2024 - Elsevier
Metal complexes of Schiff base ligands (exhibit imine-C= N-functional group) derived from
thiosemicarbazide and 1, 3, 4 thiadiazole have attracted the attention of researchers on …
thiosemicarbazide and 1, 3, 4 thiadiazole have attracted the attention of researchers on …
Synthesis, biological evaluation, and in silico study of novel library sulfonates containing quinazolin‐4(3H)‐one derivatives as potential aldose reductase inhibitors
A series of novel sulfonates containing quinazolin‐4 (3 H)‐one ring derivatives was
designed to inhibit aldose reductase (ALR2, EC 1.1. 1.21). Novel quinazolinone derivatives …
designed to inhibit aldose reductase (ALR2, EC 1.1. 1.21). Novel quinazolinone derivatives …