Functional gastrointestinal disorders—recently renamed into disorders of gut–brain
interaction—such as irritable bowel syndrome and functional dyspepsia are highly prevalent …

The gut mucosa of human is covered by mucus, functioning as a crucial defense line for the
intestine against external stimuli and pathogens. Mucin2 (MUC2) is a subtype of secretory …

Objective Functional dyspepsia (FD) is a complex disorder, with debilitating epigastric
symptoms. Evidence suggests alterations in gastrointestinal (GI) motility, visceral …

The gut-brain axis describes a bidirectional interplay within the enteric environment between
the intestinal epithelium, the mucosal immune system, and the microbiota with the enteric …

Postprandial, or meal-related, symptoms, such as abdominal pain, early satiation, fullness or
bloating, are often reported by patients with disorders of gut-brain interaction, including …

Background Functional dyspepsia (FD) is a common and debilitating gastrointestinal
disorder attributed to altered gut‐brain interactions. While the etiology of FD remains …

Background Functional dyspepsia is characterised by chronic symptoms of post-prandial
distress or epigastric pain not associated with defined structural pathology. Increased …

Significance: Inflammasomes are multimeric complexes that, as part of the innate immune
response, sense a wide range of pathogenic and sterile stimuli. They consist of three …

A malignant tumor is a complex systemic disease involving the nervous system, which
regulates nerve signals. Cancer neuroscience is a field that explores the interactions …

Background Irritable bowel syndrome (IBS) is considered a disorder of gut-brain interaction
(DGBI), presenting as chronic abdominal pain and altered defaecation. Symptoms are often …