Microglia are the main resident immune cells of the nervous system and as such they are
involved in multiple roles ranging from tissue homeostasis to response to insults and circuit …

Albinism is a pigment disorder affecting eye, skin and/or hair. Patients usually have
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …

This chapter provides an outline of the organization of the mammalian retina, with a strong
focus on primate vision and in the context of a nearly complete cellular catalog and …

Complex alterations in the anatomy of outer retinal pathways accompany photoreceptor
degeneration in the rd1 mouse model of retinitis pigmentosa, whereas inner retinal neurons …

The complex network of neuronal cells in the retina makes it a potential target of neuronal
toxicity–a risk factor for visual loss. With growing use of nanoparticles (NPs) in commercial …

Tissue specific extracellular matrices (ECM) provide structural support and enable access to
molecular signals and metabolites, which are essential for directing stem cell renewal and …

In a subset of hereditary retinal diseases, early photoreceptor degeneration causes rapidly
progressive blindness in children. To better understand how retinal development may …

Our sense of sight relies on photoreceptors, which transduce photons into the nervous
system's electrochemical interpretation of the visual world. These precious photoreceptors …

Nanoparticles are nanometer-scaled particles, and can be utilized in the form of
nanocapsules, nanoconjugates, or nanoparticles themselves for the treatment of …

Background Retinopathy of prematurity (ROP) is a major cause of vision impairment in low
birth weight infants. While previous work has focused on defining the mechanisms of …