Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Background Alzheimer's disease is the most prevalent cause of dementia in the elderly.
Neuronal death and synaptic dysfunctions are considered the main hallmarks of this …

A crude rat liver mitochondrial fraction that was capable of the rapid, linked synthesis of
phosphatidylserine (PtdSer), phosphatidylethanolamine (PtdEtn), and phosphatidylcholine …

The endoplasmic reticulum (ER) has a quality-control system for'proof-reading'newly
synthesized proteins, so that only native conformers reach their final destinations. Non …

One of the challenges of contemporary cell biology is to unravel how the molecular
composition of the different cellular compartments is generated and maintainedduring the …

New textbooks at all levels of chemistry appear with great regularity. Some fields like basic
biochemistry, organic reaction mechanisms, and chemical thermody namics are well …

Using a selection for spontaneous mutants that mislocalize a vacuolar carboxypeptidase Y
(CPY)-invertase fusion protein to the cell surface, we identified vacuolar protein targeting …

To automate examination of massive amounts of sequence data for biological function, it is
important to computerize interpretation based on empirical knowledge of sequence-function …

A variety of quality control mechanisms operate in the endoplasmic reticulum and in
downstream compartments of the secretory pathway to ensure the fidelity and regulation of …

Monensin, a monovalent ion-selective ionophore, facilitates the transmembrane exchange
of principally sodium ions for protons. The outer surface of the ionophore-ion comples is …