The porcine innate immune system: an update

KH Mair, C Sedlak, T Käser, A Pasternak… - Developmental & …, 2014 - Elsevier
Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …

The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease

L Fairbairn, R Kapetanovic, DP Sester… - Journal of leukocyte …, 2011 - academic.oup.com
The biology of cells of the mononuclear phagocyte system has been studied extensively in
the mouse. Studies of the pig as an experimental model have commonly been consigned to …

Chronic ingestion of deoxynivalenol and fumonisin, alone or in interaction, induces morphological and immunological changes in the intestine of piglets

APFL Bracarense, J Lucioli, B Grenier… - British Journal of …, 2012 - cambridge.org
Deoxynivalenol (DON) and fumonisins (FB) are mycotoxins produced by Fusarium species,
which naturally co-occur in animal diets. The gastrointestinal tract represents the first barrier …

Mucosal immunity and protective efficacy of intranasal inactivated influenza vaccine is improved by chitosan nanoparticle delivery in pigs

S Dhakal, S Renu, S Ghimire… - Frontiers in …, 2018 - frontiersin.org
Annually, swine influenza A virus (SwIAV) causes severe economic loss to swine industry.
Currently used inactivated SwIAV vaccines administered by intramuscular injection provide …

QseC Mediates Salmonella enterica Serovar Typhimurium Virulence In Vitro and In Vivo

CG Moreira, D Weinshenker… - Infection and immunity, 2010 - journals.asm.org
ABSTRACT The autoinducer-3 (AI-3)/epinephrine (Epi)/norepinephrine (NE) interkingdom
signaling system mediates chemical communication between bacteria and their mammalian …

The low intestinal and hepatic toxicity of hydrolyzed fumonisin B1 correlates with its inability to alter the metabolism of sphingolipids

B Grenier, APFL Bracarense, HE Schwartz… - Biochemical …, 2012 - Elsevier
Fumonisins are mycotoxins frequently found as natural contaminants in maize, where they
are produced by the plant pathogen Fusarium verticillioides. They are toxic to animals and …

Zearalenone mycotoxin affects immune mediators, MAPK signalling molecules, nuclear receptors and genome-wide gene expression in pig spleen

GC Pistol, C Braicu, M Motiu, MA Gras, DE Marin… - PLoS …, 2015 - journals.plos.org
The toxicity of zearalenone (ZEA) was evaluated in swine spleen, a key organ for the innate
and adaptative immune response. Weaned pigs were fed for 18 days with a control or a ZEA …

Deoxynivalenol induces apoptosis and inflammation in the liver: Analysis using precision-cut liver slices

AL Hasuda, E Person, AK Khoshal, S Bruel… - Food and Chemical …, 2022 - Elsevier
Deoxynivalenol (DON) is one of the most common mycotoxins in cereals and their by-
products. Its adverse effects on animal and human health have been extensively studied in …

Deoxynivalenol as a new factor in the persistence of intestinal inflammatory diseases: an emerging hypothesis through possible modulation of Th17-mediated …

PM Cano, J Seeboth, F Meurens, J Cognie, R Abrami… - PLoS …, 2013 - journals.plos.org
Background/Aims Deoxynivalenol (DON) is a mycotoxin produced by Fusarium species
which is commonly found in temperate regions worldwide as a natural contaminant of …

Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs

IA Naqid, JP Owen, BC Maddison, DS Gardner… - Animal Feed Science …, 2015 - Elsevier
Salmonellosis causes significant economic losses to the pig industry and contaminated pork
products are an important source of Salmonella for humans. The EU ban on the use of …