CC chemokines, a subfamily of 27 chemotactic cytokines, are a component of intercellular
communication, which is crucial for the functioning of the tumor microenvironment. Although …

Aptamers are RNA/DNA oligonucleotide molecules that specifically bind to a targeted
complementary molecule. As potential recognition elements with promising diagnostic and …

Background The powerful 'graft versus leukemia'effect thought partly responsible for the
therapeutic effect of allogeneic hematopoietic cell transplantation in acute myeloid leukemia …

Acute myeloid leukemia (AML) is a highly heterogeneous malignancy of the blood and bone
marrow, characterized by clonal expansion of myeloid stem and progenitor cells and rapid …

Acute Myeloid Leukaemia (AML) is a commonly occurring severe haematological
malignancy, with most patients exhibiting sub-optimal clinical outcomes. Therapy resistance …

The bone marrow (BM) is the primary site of adult haematopoiesis, where stromal elements
(eg fibroblasts and mesenchymal stem cells [MSCs]) work in concert to support blood cell …

Simple Summary AML is a type of leukemia with a very unfavorable prognosis. Some of the
new therapeutic targets that are being investigated by researchers worldwide are …

The study of the cellular secretome using proteomic techniques continues to capture the
attention of the research community across a broad range of topics in biomedical research …

Dysregulation of immune-checkpoint receptors has been reported at diagnosis of chronic
myeloid leukemia (CML), however, their role in the maintenance of remission after tyrosine …

Recent studies have provided several insights into acute myeloid leukemia. Studies based
on molecular biology have identified eight functional mutations involved in leukemogenesis …