Saliva diagnostics

T Nonaka, DTW Wong - Annual Review of Analytical Chemistry, 2022 - annualreviews.org
Cancer remains one of the leading causes of death, and early detection of this disease is
crucial for increasing survival rates. Although cancer can be diagnosed following tissue …

Saliva as a diagnostic fluid

D Malamud - Dental Clinics, 2011 - dental.theclinics.com
Saliva is a clinically informative, biologic fluid (biofluid) that is useful for novel approaches to
prognosis, laboratory or clinical diagnosis, and monitoring and management of patients with …

Identification and proteomic profiling of exosomes in human cerebrospinal fluid

JM Street, PE Barran, CL Mackay, S Weidt… - Journal of translational …, 2012 - Springer
Background Exosomes are released from multiple cell types, contain protein and RNA
species, and have been exploited as a novel reservoir for disease biomarker discovery …

Saliva: diagnostics and therapeutic perspectives

N Spielmann, DT Wong - Oral diseases, 2011 - Wiley Online Library
Oral Diseases (2011) 17, 345–354 For the past two decades, salivary diagnostic
approaches have been developed to monitor oral diseases such as periodontal diseases …

Comparative human salivary and plasma proteomes

JA Loo, W Yan, P Ramachandran… - Journal of dental …, 2010 - journals.sagepub.com
The protein compositions, or the proteomes, found in human salivary and plasma fluids are
compared. From recent experimental work by many laboratories, a catalogue of 2290 …

Promising applications of human-derived saliva biomarker testing in clinical diagnostics

M Song, H Bai, P Zhang, X Zhou, B Ying - International Journal of Oral …, 2023 - nature.com
Saliva testing is a vital method for clinical applications, for its noninvasive features, richness
in substances, and the huge amount. Due to its direct anatomical connection with oral …

Saliva diagnostics: salivaomics, saliva exosomics, and saliva liquid biopsy

T Nonaka, DTW Wong - The Journal of the American Dental Association, 2023 - Elsevier
Background Each day, humans produce approximately 0.5 through 1.5 liters of saliva, a
biofluid that is rich in biological omic constituents. Our lack of understanding how omic …

Blood, sweat, and tears: develo** clinically relevant protein biosensors for integrated body fluid analysis

SR Corrie, JW Coffey, J Islam, KA Markey, MAF Kendall - Analyst, 2015 - pubs.rsc.org
Biosensors are being developed to provide rapid, quantitative, diagnostic information to
clinicians in order to help guide patient treatment, without the need for centralised laboratory …

Review insights on salivary proteomics biomarkers in oral cancer detection and diagnosis

VR Umapathy, PM Natarajan, B Swamikannu - Molecules, 2023 - mdpi.com
Early detection is crucial for the treatment and prognosis of oral cancer, a potentially lethal
condition. Tumor markers are abnormal biological byproducts produced by malignant cells …

Saliva metabolomics opens door to biomarker discovery, disease diagnosis, and treatment

A Zhang, H Sun, X Wang - Applied biochemistry and biotechnology, 2012 - Springer
Metabolomics is the systematic study of the unique chemical fingerprints of low molecular
weight endogenous metabolites or metabolite profiles in a biological sample. Metabolites …