Antimicrobial peptides (AMPs) are widely expressed and rapidly induced at epithelial
surfaces to repel assault from diverse infectious agents including bacteria, viruses, fungi and …

Defensins comprise one of the largest groups of host defence peptides, present throughout
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …

The concept of antimicrobial peptides (AMPs) as potent pharmaceuticals is firmly
established in the literature, and most research articles on this topic conclude by stating that …

Abstract β-defensins play a dual role during immune response. Their direct antimicrobial
properties contribute to the local innate immune response by combating microbial invasions …

Polihexanide is a broad-spectrum antiseptic with excellent tolerance and a low-risk profile.
The physicochemical action on the bacterial envelope prevents or impedes the development …

Paneth cells at the base of small intestinal crypts of Lieberkühn secrete high levels of α-
defensins in response to cholinergic and microbial stimuli. Paneth cell α-defensins are …

Over the last years, antimicrobial peptides (AMPs) have been the focus of intense research
toward the finding of a viable alternative to current antifungal drugs. Defensins are one of the …

Abstract β‐defensins are antimicrobial peptides with an essential role in the innate immune
response. In addition β‐defensins can also chemoattract cells involved in adaptive immunity …

While proteases are essential in gastrointestinal physiology, accumulating evidence
indicates that dysregulated proteolysis plays a pivotal role in the pathophysiology of …

Background Tumor-associated macrophages (TAMs) constitute a significant part of
infiltrating inflammatory cells that are frequently correlated with progression and poor …