Effect of zeta potential on the properties of nano-drug delivery systems-a review (Part 2)

S Honary, F Zahir - Tropical journal of pharmaceutical research, 2013‏ - ajol.info
The zeta potential (ZP) of colloidal systems and nano-medicines, as well as their particle
size exert a major effect on the various properties of nano-drug delivery systems. Not only …

Nanoparticles for drug delivery to the anterior segment of the eye

DR Janagam, L Wu, TL Lowe - Advanced drug delivery reviews, 2017‏ - Elsevier
Commercially available ocular drug delivery systems are effective but less efficacious to
manage diseases/disorders of the anterior segment of the eye. Recent advances in …

In situ gelling systems: a strategy to improve the bioavailability of ophthalmic pharmaceutical formulations

H Almeida, MH Amaral, P Lobão, JMS Lobo - Drug discovery today, 2014‏ - Elsevier
The low therapeutic efficacy exhibited by conventional ophthalmic solutions owing to
precorneal elimination of the drug, drainage by gravity, nasolacrimal drainage, conjunctival …

Polymer-based carriers for ophthalmic drug delivery

JC Imperiale, GB Acosta, A Sosnik - Journal of controlled release, 2018‏ - Elsevier
Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …

Optimization to development of chitosan decorated polycaprolactone nanoparticles for improved ocular delivery of dorzolamide: In vitro, ex vivo and toxicity …

MS Shahab, M Rizwanullah, S Alshehri… - International journal of …, 2020‏ - Elsevier
The present research work was designed to develop dorzolamide-loaded chitosan-coated
polycaprolactone nanoparticles (DRZ-CS-PCL-NPs) for improved ocular delivery. The …

[ספר][B] Chitin and chitosan derivatives: advances in drug discovery and developments

SK Kim - 2013‏ - books.google.com
This book presents current research trends in the synthesis of chitin and chitosan
derivatives, their biological activities, and their biomedical applications. Part I discusses …

[ספר][B] Nanomaterials for medical applications

Z Aguilar - 2012‏ - books.google.com
This title covers recent advances in a variety of biomedical applications of nanostructured
materials, as the field evolves from prototype device to real-world application. It presents the …

Chitosan-coated PLGA nanoparticles of bevacizumab as novel drug delivery to target retina: optimization, characterization, and in vitro toxicity evaluation

J Pandit, Y Sultana, M Aqil - Artificial cells, nanomedicine, and …, 2017‏ - Taylor & Francis
In several ocular diseases, the vascular endothelial growth factor (VEGF) level has been
found to be upregulated. Bevacizumab, an anti-VEGF drug, is the most commonly used off …

Topical delivery of ocular therapeutics: carrier systems and physical methods

JG Souza, K Dias, TA Pereira… - Journal of Pharmacy …, 2014‏ - academic.oup.com
Objective The basic concepts, major mechanisms, technological developments and
advantages of the topical application of lipid-based systems (microemulsions …

Chitosan coated PLGA nanoparticles amplify the ocular hypotensive effect of forskolin: Statistical design, characterization and in vivo studies

N Khan, K Khanna, A Bhatnagar, FJ Ahmad… - International Journal of …, 2018‏ - Elsevier
Purpose Enhancing the ocular hypotensive effect of forskolin (FK) by means of
biodegradable chitosan (CS) coated poly lactic-co-glycolic acid (PLGA) nanoparticles …