Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

Disrupted protein folding or decreased protein stability can lead to the accumulation of
(partially) un‐or misfolded proteins, which ultimately cause the formation of protein …

Fibrillar aggregates of the amyloid-β protein (Aβ) are the main component of the senile
plaques found in brains of patients with Alzheimer's disease (AD). Development of probes …

Fluorescence imaging in the second near‐infrared (NIR‐II) window holds great promise for
in vivo visualization of amyloid‐β (Aβ) pathology, which can facilitate characterization and …

The precise detection of atherosclerosis has been a research hot point since its importance
in the diagnosis of cardiovascular diseases. Here we synthesized a near-infrared …

Alzheimer's disease (AD) and Parkinson's disease (PD) are chronic neurodegenerative
diseases with high morbidity and mortality. Homocysteine (Hcy), cysteine (Cys), and …

Imaging amyloid-beta (Aβ) aggregation is critical for understanding the pathology and aiding
the pre-symptomatic intervention of Alzheimer's disease (AD). Amyloid aggregation consists …

Amyloid fibril is an important pharmaceutical target for diagnostic and therapeutic treatment
of neurodegenerative diseases. However, rational design of chemical compounds that …

Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …

Visualization of the brain in its native environment is important for understanding common
brain diseases. Herein, bright luminogens with remarkable aggregation‐induced emission …