The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Inflammation is a comprehensive array of physiological response to a foreign organism,
including human pathogens, dust particles, and viruses. Inflammations are mainly divided …

Persistent, unresolved inflammation in the liver represents a key trigger for hepatic injury
and fibrosis in various liver diseases and is controlled by classically activated …

Sustained hepatic inflammation is an important factor in progression of chronic liver
diseases, including hepatitis C or non-alcoholic steatohepatitis. Liver inflammation is …

Non-alcoholic fatty liver disease (NAFLD), the most prevalent liver pathology worldwide, is
intimately linked with obesity and type 2 diabetes. Liver inflammation is a hallmark of NAFLD …

The liver is essential for inducing immunological tolerance toward harmless antigens to
maintain immune system homeostasis. However, the precise cellular mechanisms of …

Cellular crosstalk is a process through which a message is transmitted within an individual
cell (intracellular crosstalk) or between different cells (intercellular crosstalk). Intercellular …

Resident and recruited macrophages are key players in the homeostatic function of the liver
and in its response to tissue damage. In response to environmental signals, macrophages …

Liver allograft rejection remains a significant cause of morbidity and graft failure in liver
transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens …

Background Human menstrual blood-derived stem cells (MenSCs) are a novel source of
MSCs that provide the advantage of being easy to collect and isolate. Exosomes contain …