Chronic pain affects a large part of the population causing functional disability, being often
associated with coexisting psychological disorders, such as depression and anxiety …

Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …

Chronic pain is one of the most prevalent health problems in our modern world, with millions
of people debilitated by conditions such as back pain, headache and arthritis. To address …

The parabrachial nucleus (PBN) has long been recognized as a sensory relay receiving an
array of interoceptive and exteroceptive inputs relevant to taste and ingestive behavior, pain …

Scientific evidence supports the notion that migraine pathophysiology involves inherited
alteration of brain excitability, intracranial arterial dilatation, recurrent activation, and …

Clinical pain is a serious public health issue. Treatment of pain-related suffering requires
knowledge of how pain signals are initially interpreted and subsequently transmitted and …

The state of our understanding of the interaction between pain and the brain is undergoing a
veritable revolution, with new surprising observations accumulating at a fast pace. A cursory …

Pain is a highly complex and individual experience with biological, psychological and social
(biopsychosocial) contributions. Pain is associated with activity within the nervous system …

In this paper we present a method to segment four brainstem structures (midbrain, pons,
medulla oblongata and superior cerebellar peduncle) from 3D brain MRI scans. The …