Preterm birth and sustained inflammation: consequences for the neonate

A Humberg, I Fortmann, B Siller, MV Kopp… - Seminars in …, 2020 - Springer
Almost half of all preterm births are caused or triggered by an inflammatory process at the
feto-maternal interface resulting in preterm labor or rupture of membranes with or without …

Influence of infection during pregnancy on fetal development

KMA Waldorf, RM McAdams - Reproduction, 2013 - rep.bioscientifica.com
Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited
sequelae depending on the pathogen. Here, we consider the role of infection during …

Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes

R Romero, J Miranda, P Chaemsaithong… - The journal of …, 2015 - Taylor & Francis
Objective: The objectives of this study were to:(1) determine the amniotic fluid (AF)
microbiology of patients with preterm prelabor rupture of membranes (PROM); and (2) …

The consequences of chorioamnionitis: preterm birth and effects on development

R Galinsky, GR Polglase, SB Hooper… - Journal of …, 2013 - Wiley Online Library
Preterm birth is a major cause of perinatal mortality and long‐term morbidity.
Chorioamnionitis is a common cause of preterm birth. Clinical chorioamnionitis …

Preterm birth, intrauterine infection, and fetal inflammation

MW Kemp - Frontiers in immunology, 2014 - frontiersin.org
Preterm birth (PTB)(delivery before 37 weeks' gestation) is a leading cause of neonatal
death and disease in industrialized and develo** countries alike. Infection (most notably …

Improving pregnancy outcomes in humans through studies in sheep

JL Morrison, MJ Berry, KJ Botting… - American Journal …, 2018 - journals.physiology.org
Experimental studies that are relevant to human pregnancy rely on the selection of
appropriate animal models as an important element in experimental design. Consideration …

Pathology of bronchopulmonary dysplasia

JJ Coalson - Seminars in perinatology, 2006 - Elsevier
Over the past three decades, advances in prenatal and neonatal intensive care have
contributed to marked improvements in survival rates for extremely immature infants born …

Oxidative stress and bronchopulmonary dysplasia

S Perrone, ML Tataranno… - Journal of clinical …, 2012 - journals.lww.com
Bronchopulmonary dysplasia (BPD) is the major cause of pulmonary disease in infants. The
pathophysiology and management of BPD changed with the improvement of neonatal …

Prenatal inflammation and lung development

BW Kramer, S Kallapur, J Newnham… - Seminars in fetal and …, 2009 - Elsevier
Prenatal exposure of very low birth weight infants to chronic indolent chorioamnionitis with
organisms such as mycoplasma and ureaplasma is frequent. Chorioamnionitis is …

Brief, large tidal volume ventilation initiates lung injury and a systemic response in fetal sheep

NH Hillman, TJM Moss, SG Kallapur… - American journal of …, 2007 - atsjournals.org
Rationale: Premature infants are exposed to potentially injurious ventilation in the delivery
room. Assessments of lung injury are confounded by effects of subsequent ventilatory …