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Biocatalysis: enzymatic synthesis for industrial applications
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …
Fatty acids and their derivatives as renewable platform molecules for the chemical industry
U Biermann, UT Bornscheuer… - Angewandte Chemie …, 2021 - Wiley Online Library
Oils and fats of vegetable and animal origin remain an important renewable feedstock for the
chemical industry. Their industrial use has increased during the last 10 years from 31 to 51 …
chemical industry. Their industrial use has increased during the last 10 years from 31 to 51 …
Biocatalytic reduction reactions from a chemist's perspective
Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …
Reductive enzyme cascades for valorization of polyethylene terephthalate deconstruction products
To better incentivize the collection of plastic wastes, chemical transformations must be
developed that add value to plastic deconstruction products. Polyethylene terephthalate …
developed that add value to plastic deconstruction products. Polyethylene terephthalate …
Carboxylic acid reductase enzymes (CARs)
M Winkler - Current opinion in chemical biology, 2018 - Elsevier
Highlights•Carboxylate reductases (CARs) catalyze the selective one step reduction of an
acid to an aldehyde.•The substrate scope of CARs is broad.•CARs have been implemented …
acid to an aldehyde.•The substrate scope of CARs is broad.•CARs have been implemented …
One-pot biocatalytic transformation of adipic acid to 6-aminocaproic acid and 1, 6-hexamethylenediamine using carboxylic acid reductases and transaminases
TP Fedorchuk, AN Khusnutdinova… - Journal of the …, 2019 - ACS Publications
Production of platform chemicals from renewable feedstocks is becoming increasingly
important due to concerns on environmental contamination, climate change, and depletion …
important due to concerns on environmental contamination, climate change, and depletion …
Developed and emerging 1, 4-butanediol commercial production strategies: forecasting the current status and future possibility
Butanediol (1, 4-BDO) is a valuable industrial chemical that is primarily produced via several
energy-intensive petrochemical processes based on fossil-based raw materials, leading to …
energy-intensive petrochemical processes based on fossil-based raw materials, leading to …
Advances in research on the bio-production of 1, 4-butanediol by the engineered microbes
H Guo, H Liu, Y **, R Zhang, Y Yu, L Deng… - Biochemical Engineering …, 2022 - Elsevier
butanediol (1, 4-BDO) is an important building block in the chemical industry, which can be
used to produce different products including tetrahydrofuran, γ-butyrolactone, polybutylene …
used to produce different products including tetrahydrofuran, γ-butyrolactone, polybutylene …
Enhancing Gastrodin Production in Yarrowia lipolytica by Metabolic Engineering
Y Wu, S Li, B Sun, J Guo, M Zheng, A Li - ACS Synthetic Biology, 2024 - ACS Publications
Gastrodin, 4-hydroxybenzyl alcohol-4-O-β-D-glucopyranoside, has been widely used in the
treatment of neurogenic and cardiovascular diseases. Currently, gastrodin biosynthesis is …
treatment of neurogenic and cardiovascular diseases. Currently, gastrodin biosynthesis is …
ATP regeneration by a single polyphosphate kinase powers multigram-scale aldehyde synthesis in vitro
ATP recycling systems are required to avoid the addition of stoichiometric quantities of
cofactor and facilitate industrial implementation of ATP-dependent enzymes. One factor that …
cofactor and facilitate industrial implementation of ATP-dependent enzymes. One factor that …