Advances in neuroscience identified addiction as a chronic brain disease with strong
genetic, neurodevelopmental, and sociocultural components. We here discuss the circuit …

Background Despite initial reports of a decline in use in the early 2000s, methamphetamine
remains a significant public health concern with known neurotoxic and neurocognitive …

Small molecule neurotensin receptor 1 (NTSR1) agonists have been pursued for more than
40 years as potential therapeutics for psychiatric disorders, including drug addiction. Clinical …

Methamphetamine (MA) is one of the most commonly abused illicit substances worldwide.
Among other problems, abuse of the drug has been associated with reduced cognitive …

Despite aggressive efforts to contain it, methamphetamine use disorder continues to be
major public health problem; and with generic behavioral therapies still the mainstay of …

Diverse intellectual functions including memory are some important aspects of cognition.
Dopamine is a neurotransmitter of the catecholamine family, which contributes to the …

Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses
through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation …

Methamphetamine use disorder is associated with striatal dopaminergic deficits that have
been linked to poor treatment outcomes, identifying these deficits as an important …

Gambling is pertinent to neuroscience research for at least two reasons. First, gambling is a
naturalistic and pervasive example of risky decision making, and thus gambling games can …

Background Long-term use of MA has been associated with cognitive dysfunction in several
domains. Neuroimaging studies have also reported structural, metabolic, and functional …