Glucose and fatty acids are the major sources of energy for human body. Cholesterol, the
most abundant sterol in mammals, is a key component of cell membranes although it does …

Membrane trafficking pathways are essential for the viability and growth of cells, and play a
major role in the interaction of cells with their environment. In this At a Glance article and …

Coat proteins play multiple roles in the life cycle of a membrane‐bound transport
intermediate, functioning in lipid bilayer remodeling, cargo selection and targeting to an …

Protein coats are supramolecular complexes that assemble on the cytosolic face of
membranes to promote cargo sorting and transport carrier formation in the endomembrane …

Zika virus (ZIKV) infection can be associated with neurological pathologies, such as
microcephaly in newborns and Guillain-Barre syndrome in adults. Effective therapeutics are …

The hereditary anemias are a relatively heterogeneous set of disorders that can show wide
clinical and genetic heterogeneity, which often hampers correct clinical diagnosis. The …

Secretory cargo is recognized, concentrated and trafficked from endoplasmic reticulum (ER)
exit sites (ERES) to the Golgi. Cargo export from the ER begins when a series of highly …

Abstract Endoplasmic reticulum (ER)‐to‐Golgi trafficking is an essential and highly
conserved cellular process. The coat protein complex‐II (COPII) arm of the trafficking …

The cytoplasmic coat protein complex-II (COPII) is evolutionarily conserved machinery that is
essential for efficient trafficking of protein and lipid cargos. How the COPII machinery is …

Hematopoiesis, or the process of blood cell production, is a paradigm of multi‐lineage
cellular differentiation that has been extensively studied, yet in many aspects remains …