In the second half of the eighteenth century, Schlosser and Ellis described the colonial
ascidian Botryllus schlosseri garnering the interest of scientists around the world. In the …

Adult stem cells (ASCs) in vertebrates and model invertebrates (eg Drosophila
melanogaster) are typically long‐lived, lineage‐restricted, clonogenic and quiescent cells …

The mechanisms that sustain stem cells are fundamental to tissue maintenance. Here, we
identify" cell islands"(CIs) as a niche for putative germ and somatic stem cells in Botryllus …

Stem cell populations exist in" niches" that hold them and regulate their fate decisions.
Identification and characterization of these niches is essential for understanding stem cell …

Germ cell sequestering in Animalia is enlightened by either, launching true germ line along
epigenetic or preformistic modes of development, or by somatic embryogenesis, where no …

Allorecognition has been well-studied in the context of vertebrate adaptive immunity and
recognition of the Major Histocompatibility Complex (MHC), which is the central event of …

Ontologies provide an important resource to integrate information. For developmental
biology and comparative anatomy studies, ontologies of a species are used to formalize and …

Regeneration is widely distributed among the metazoans. However, clear differences exist
as to the degree of regenerative capacity: some phyla can only replace missing body parts …

Environmental Risk Assessment (ERA) often relies on a restricted set of species as bio-
indicators, introducing uncertainty when modeling complex environmental variables. This …

Harsh environments enforce the expression of behavioural, morphological, physiological,
and reproductive rejoinders, including torpor. Here we study the morphological, cellular, and …