Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

Tumor metastasis is a multi-step process by which tumor cells disseminate from their primary
site and form secondary tumors at a distant site. And metastasis is the major cause of death …

The emerging concept of cancer stem cells (CSCs) as the key driver behind carcinogenesis,
progression, and diversity has displaced the prior model of a tumor composed of cells with …

The great majority of cancer deaths are due to metastasis, which remains a poorly
understood pathological process. The formation of a metastasis reflects a succession of …

Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies with a high
incidence and mortality rate. An essential challenge in colorectal cancer management is to …

Colorectal cancer (CRC) is the third most common cancer affecting people. The discovery of
new, non-invasive, specific, and sensitive molecular biomarkers for CRC may assist in the …

MicroRNAs play an important regulatory role in carcinogenesis and cancer metastasis.
Different members of let-7 family have been reported to be decreased in human lung tumors …

Background The upregulated expression of CXCL1 has been validated in colorectal cancer
patients. As a potential biotherapeutic target for colorectal cancer, the mechanism by which …

Regulation of microRNA (miRNA) expression has been extensively studied with respect to
colorectal cancer (CRC), since CRC is one of the leading causes of cancer mortality …

Gene expression is in part regulated by microRNAs (miRNAs). This review summarizes the
current knowledge of miRNAs in colorectal cancer (CRC); their role as growth regulators, the …