The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …

Drug resistance remains the major cause of cancer treatment failure especially at the late
stage of the disease. However, based on their versatile chemistry, metal and metalloid …

The increasing impact of organometallic complexes of group 8–10 metals academically and
industrially over the years demonstrates remarkable progress in harvesting useful reagents …

This review focuses on studies of coordination and organometallic compounds as potential
chemotherapeutics against triple negative breast cancer (TNBC) which has one of the …

The emergence of multidrug resistance (MDR) is the leading cause of mortality in patients
with breast cancer. Overexpressed P-glycoprotein (P-gp) that can pump out …

Since the discovery of the anticancer potential of ruthenium-based complexes, several
species were reported as promising candidates for the treatment of breast cancer, which …

The clinical efficacy of current cancer therapies falls short, and there is a pressing demand to
integrate new targets with conventional therapies. Autophagy, a highly conserved self …

Cisplatin and derivatives are highly effective in the treatment of a wide range of cancer
types; however, these metallodrugs display low selectivity, leading to severe side effects …

Cancer is a major health concern and a leading cause of death worldwide. Among all
cancer types, breast cancer has the highest incidence rate. The treatment of breast cancer …