[HTML][HTML] A Glimpse at the Size of the Fetal Liver—Is It Connected with the Evolution of Gestational Diabetes?

MA Cozma, MA Găman, EC Dobrică… - International Journal of …, 2021 - mdpi.com
Gestational diabetes mellitus (GDM) is defined as an impairment of glucose tolerance,
manifested by hyperglycemia, which occurs at any stage of pregnancy. GDM is more …

Maternal insulin resistance in pregnancy is associated with fetal fat deposition: findings from a longitudinal study

S Ikenoue, F Waffarn, K Sumiyoshi, M Ohashi… - American Journal of …, 2023 - Elsevier
Background Newborns exhibit substantial variation in fat mass accretion over gestation.
These individual differences in newborn adiposity extend into infancy and childhood and …

The effect of a high-fat diet on the fatty acid composition in the hearts of mice

A Pakiet, A Jakubiak, P Mierzejewska, A Zwara, I Liakh… - Nutrients, 2020 - mdpi.com
The Western diet can lead to alterations in cardiac function and increase cardiovascular risk,
which can be reproduced in animal models by implementing a high-fat diet (HFD). However …

[HTML][HTML] Maternal diet intervention before pregnancy primes offspring lipid metabolism in liver

Y Zhou, H Peng, H Xu, J Li, M Golovko, H Cheng… - Laboratory …, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has a developmental origin and is influenced in
utero. We aimed to evaluate if maternal diet intervention before pregnancy would be …

The application of in utero magnetic resonance imaging in the study of the metabolic and cardiovascular consequences of the developmental origins of health and …

SA Giza, S Sethi, LM Smith, MEET Empey… - … origins of health and …, 2021 - cambridge.org
Observing fetal development in utero is vital to further the understanding of later-life
diseases. Magnetic resonance imaging (MRI) offers a tool for obtaining a wealth of …

Pregnancies complicated by gestational diabetes and fetal growth restriction: an analysis of maternal and fetal body composition using magnetic resonance imaging

KM Strobel, SG Kafali, SF Shih, AM Artura… - Journal of …, 2023 - nature.com
Introduction Maternal body composition may influence fetal body composition. Objective The
objective of this pilot study was to investigate the relationship between maternal and fetal …

A free-choice high-fat, high-sucrose diet induces hyperphagia, obesity, and cardiovascular dysfunction in female cycling and pregnant rats

H Ahmed, JL Hannan, JW Apolzan… - American Journal …, 2019 - journals.physiology.org
The main objective of these studies was to characterize metabolic, body composition, and
cardiovascular responses to a free-choice high-fat, high-sucrose diet in female cycling and …

Motion‐robust, high‐SNR liver fat quantification using a 2D sequential acquisition with a variable flip angle approach

R Zhao, Y Zhang, X Wang, TJ Colgan… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose Chemical shift encoded (CSE)‐MRI enables quantification of proton‐density fat
fraction (PDFF) as a biomarker of liver fat content. However, conventional 3D Cartesian CSE …

Feasibility of MRI quantification of myelin water fraction in the fetal guinea pig brain

S Sethi, LJ Friesen‐Waldner, TP Wade… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Fetal myelination assessment is important for understanding
neurodevelopment and neurodegeneration. Myelin water imaging (MWI) quantifies myelin …

Hepatic cytochrome P450 function is reduced by life-long Western diet consumption in guinea pig independent of birth weight

MD Wiese, AS Meakin, TJ Varcoe, JRT Darby, O Sarr… - Life Sciences, 2021 - Elsevier
Introduction Non-alcoholic fatty liver disease (NAFLD) is characterised by accumulation of
triglycerides and cholesterol within the liver and dysregulation of specific hepatic …