Neurobiology of rodent self-grooming and its value for translational neuroscience

AV Kalueff, AM Stewart, C Song, KC Berridge… - Nature Reviews …, 2016 - nature.com
Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing
pattern and is one of the most frequently performed behavioural activities in rodents. In this …

Obsessive-compulsive disorder: advances in diagnosis and treatment

ME Hirschtritt, MH Bloch, CA Mathews - Jama, 2017 - jamanetwork.com
Importance Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder associated
with significant impairment and a lifetime prevalence of 1% to 3%; however, it is often …

Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis

D Posthuma - Molecular psychiatry, 2018 - research.vu.nl
Two obsessive-compulsive disorder (OCD) genome-wide association studies (GWASs)
have been published by independent OCD consortia, the International Obsessive …

Interrogating the genetic determinants of Tourette's syndrome and other tic disorders through genome-wide association studies

D Yu, JH Sul, F Tsetsos, MS Nawaz… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Tourette's syndrome is polygenic and highly heritable. Genome-wide association
study (GWAS) approaches are useful for interrogating the genetic architecture and …

Genetics and genomics of psychiatric disease

DH Geschwind, J Flint - Science, 2015 - science.org
Large-scale genomic investigations have just begun to illuminate the molecular genetic
contributions to major psychiatric illnesses, ranging from small-effect-size common variants …

Genetics of obsessive-compulsive disorder

B Mahjani, K Bey, J Boberg, C Burton - Psychological Medicine, 2021 - cambridge.org
BackgroundObsessive-compulsive disorder (OCD) is a psychiatric disorder with multiple
symptom dimensions (eg contamination, symmetry). OCD clusters in families and decades …

Gilles de la Tourette syndrome

MM Robertson, V Eapen, HS Singer… - Nature reviews Disease …, 2017 - nature.com
Gilles de la Tourette syndrome (GTS) is a childhood-onset neurodevelopmental disorder
that is characterized by several motor and phonic tics. Tics usually develop before 10 years …

A personal 35 year perspective on Gilles de la Tourette syndrome: prevalence, phenomenology, comorbidities, and coexistent psychopathologies

MM Robertson - The Lancet Psychiatry, 2015 - thelancet.com
This Series is a personal narrative of my experience with patients with Gilles de la Tourette
syndrome and covers its definition and history since the first description in 1825 …

A comprehensive review of tic disorders in children

K Ueda, KJ Black - Journal of clinical medicine, 2021 - mdpi.com
Tics are characterized by sudden, rapid, recurrent, nonrhythmic movement or vocalization,
and are the most common movement disorders in children. Their onset is usually in …

Neuroscientifically informed formulation and treatment planning for patients with obsessive-compulsive disorder: a review

DD Dougherty, BP Brennan, SE Stewart… - Jama …, 2018 - jamanetwork.com
Importance Obsessive-compulsive disorder (OCD) is a common and often debilitating
psychiatric illness. Recent advances in the understanding of the neuroscience of OCD have …