Since the first monoclonal antibody drug, muromonab-CD3, was approved for marketing in
1986, 165 antibody drugs have been approved or are under regulatory review worldwide …

Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Background The major reasons to treat sarcoidosis are to lower the morbidity and mortality
risk or to improve quality of life (QoL). The indication for treatment varies depending on …

This is the second European Crohn's and Colitis Organisation [ECCO] evidence-based
consensus on extraintestinal manifestations [EIMs] of inflammatory bowel disease [IBD] and …

Several new treatment modalities with different mechanisms of action have been studied in
patients with Behçet's syndrome (BS). The aim of the current effort was to update the …

Antibody engineering has developed into a wide-reaching field, impacting a multitude of
industries, most notably healthcare and diagnostics. The seminal work on develo** the …

Uveitis is a complex ocular inflammatory disease with a multifactorial etiology that can result
in blindness. Although corticosteroid eye drops are the primary treatment for anterior uveitis …

For many years, oxidative stress arising from the ubiquitous production of reactive oxygen
species (ROS) has been implicated in the pathogenesis of various eye diseases. While …

The uveitides are a collection of more than 30 diseases characterized by intraocular
inflammation. Many cases of juvenile idiopathic arthritis–associated uveitis, many cases of …

Abstract Pediatric uveitis accounts for 5–10% of all uveitis. Uveitis in children differs from
adult uveitis in that it is commonly asymptomatic and can become chronic and cause …