[HTML][HTML] Remaining mysteries of molecular biology: the role of polyamines in the cell

L Miller-Fleming, V Olin-Sandoval, K Campbell… - Journal of molecular …, 2015 - Elsevier
The polyamines (PAs) spermidine, spermine, putrescine and cadaverine are an essential
class of metabolites found throughout all kingdoms of life. In this comprehensive review, we …

[HTML][HTML] Polyamine catabolism and oxidative damage

TM Stewart, TT Dunston, PM Woster… - Journal of Biological …, 2018 - Elsevier
Polyamines (PAs) are indispensable polycations ubiquitous to all living cells. Among their
many critical functions, PAs contribute to the oxidative balance of the cell. Beginning with …

Polyamine metabolism links gut microbiota and testicular dysfunction

Q Zhao, JF Huang, Y Cheng, MY Dai, WF Zhu… - Microbiome, 2021 - Springer
Background Male fertility impaired by exogenous toxins is a serious worldwide issue
threatening the health of the new-born and causing infertility. However, the metabolic …

Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism

V Olin-Sandoval, JSL Yu, L Miller-Fleming, MT Alam… - Nature, 2019 - nature.com
Both single and multicellular organisms depend on anti-stress mechanisms that enable
them to deal with sudden changes in the environment, including exposure to heat and …

The function of spermine

AE Pegg - IUBMB life, 2014 - Wiley Online Library
Polyamines play important roles in cell physiology including effects on the structure of
cellular macromolecules, gene expression, protein function, nucleic acid and protein …

FMN reduces Amyloid-β toxicity in yeast by regulating redox status and cellular metabolism

X Chen, B Ji, X Hao, X Li, F Eisele, T Nyström… - Nature …, 2020 - nature.com
Alzheimer's disease (AD) is defined by progressive neurodegeneration, with oligomerization
and aggregation of amyloid-β peptides (Aβ) playing a pivotal role in its pathogenesis. In …

The roles of polyamines in microorganisms

AÖ Gevrekci - World Journal of Microbiology and Biotechnology, 2017 - Springer
Polyamines are small polycations that are well conserved in all the living organisms except
Archae, Methanobacteriales and Halobacteriales. The most common polyamines are …

Challenges and prospects for sustainable microalga-based oil: A comprehensive review, with a focus on metabolic and genetic engineering

S Ranjbar, FX Malcata - Fuel, 2022 - Elsevier
Excessive combustion of fossil fuels for energy production, with concomitant release to the
atmosphere of huge amounts of gases bearing greenhouse effects have urged search for …

The impact of non-enzymatic reactions and enzyme promiscuity on cellular metabolism during (oxidative) stress conditions

G Piedrafita, MA Keller, M Ralser - Biomolecules, 2015 - mdpi.com
Cellular metabolism assembles in a structurally highly conserved, but functionally dynamic
system, known as the metabolic network. This network involves highly active, enzyme …

MFS transporters required for multidrug/multixenobiotic (MD/MX) resistance in the model yeast: understanding their physiological function through post-genomic …

SC Dos Santos, MC Teixeira, PJ Dias… - Frontiers in …, 2014 - frontiersin.org
Multidrug/Multixenobiotic resistance (MDR/MXR) is a widespread phenomenon with clinical,
agricultural and biotechnological implications, where MDR/MXR transporters that are …