GH and the cardiovascular system: an update on a topic at heart

J Isgaard, M Arcopinto, K Karason, A Cittadini - Endocrine, 2015 - Springer
In this review, the importance of growth hormone (GH) for the maintenance of normal cardiac
function in adult life is discussed. Physiological effects of GH and underlying mechanisms for …

Growth hormone (GH) and cardiovascular system

D Caicedo, O Díaz, P Devesa, J Devesa - International journal of …, 2018 - mdpi.com
This review describes the positive effects of growth hormone (GH) on the cardiovascular
system. We analyze why the vascular endothelium is a real internal secretion gland, whose …

Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction

RM Kanashiro-Takeuchi, K Tziomalos… - Proceedings of the …, 2010 - National Acad Sciences
Whether the growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis exerts
cardioprotective effects remains controversial; and the underlying mechanism (s) for such …

Growth hormone, acromegaly, and heart failure: an intricate triangulation

L Saccà, R Napoli, A Cittadini - Clinical endocrinology, 2003 - Wiley Online Library
Short‐term GH or IGF‐I excess provides a model of physiological cardiac growth associated
with functional advantage. The physiological nature of cardiac growth is accounted for by the …

The GH/IGF-1 axis in chronic heart failure

M Arcopinto, E Bobbio, E Bossone… - … Metabolic & Immune …, 2013 - ingentaconnect.com
The classic model of Chronic Heart Failure (CHF) is rooted in the overexpression of
neurohormonal molecules. To complement this paradigm, increasing evidence indicates …

Growth hormone prolongs survival in experimental postinfarction heart failure

A Cittadini, J Isgaard, MG Monti, C Casaburi… - Journal of the American …, 2003 - jacc.org
Objectives: We evaluated the effects of growth hormone (GH) on survival in experimental
heart failure (HF). Background: Growth hormone has been beneficial in various models of …

Aldosterone receptor blockade improves left ventricular remodeling and increases ventricular fibrillation threshold in experimental heart failure

A Cittadini, MG Monti, J Isgaard… - Cardiovascular …, 2003 - academic.oup.com
Objectives: To investigate the effects of aldosterone receptor blockade in postinfarction heart
failure. Methods: Eighty-seven rats with moderate myocardial infarction were randomized to …

MRS: a noninvasive window into cardiac metabolism

PA van Ewijk, VB Schrauwen‐Hinderling… - NMR in …, 2015 - Wiley Online Library
A well‐functioning heart requires a constant supply of a balanced mixture of nutrients to be
used for the production of adequate amounts of adenosine triphosphate, which is the main …

Protective actions of melatonin and growth hormone on the aged cardiovascular system

SD Paredes, KA Forman, C García, E Vara… - … molecular biology and …, 2014 - degruyter.com
Epidemiological studies indicate that certain aspects of lifestyle and genetics act as risk
factors for a variety of cardiovascular disorders, including coronary disease, hypertension …

Two-dimensional speckle tracking echocardiography demonstrates no effect of active acromegaly on left ventricular strain

ICM Volschan, L Kasuki, CMS Silva, ML Alcantara… - Pituitary, 2017 - Springer
Background Speckle tracking echocardiography (STE) allows for the study of myocardial
strain (ε), a marker of early and subclinical ventricular systolic dysfunction. Cardiac disease …