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Killing in the name of: T6SS structure and effector diversity
The life of bacteria is challenging, to endure bacteria employ a range of mechanisms to
optimize their environment, including deploying the type VI secretion system (T6SS). Acting …
optimize their environment, including deploying the type VI secretion system (T6SS). Acting …
Type VI Secretion System in Pathogenic Escherichia coli: Structure, Role in Virulence, and Acquisition
Bacterial pathogens utilize a myriad of mechanisms to invade mammalian hosts, damage
tissue sites, and evade the immune system. One essential strategy of Gram-negative …
tissue sites, and evade the immune system. One essential strategy of Gram-negative …
Assembly and subcellular localization of bacterial type VI secretion systems
Bacteria need to deliver large molecules out of the cytosol to the extracellular space or even
across membranes of neighboring cells to influence their environment, prevent predation …
across membranes of neighboring cells to influence their environment, prevent predation …
Cryo-EM structure and assembly of an extracellular contractile injection system
Contractile injection systems (CISs) are cell-puncturing nanodevices that share ancestry
with contractile tail bacteriophages. Photorhabdus virulence cassette (PVC) represents one …
with contractile tail bacteriophages. Photorhabdus virulence cassette (PVC) represents one …
Conserved and Diverse Traits of Adhesion Devices from Siphoviridae Recognizing Proteinaceous or Saccharidic Receptors
Bacteriophages can play beneficial roles in phage therapy and destruction of food
pathogens. Conversely, they play negative roles as they infect bacteria involved in …
pathogens. Conversely, they play negative roles as they infect bacteria involved in …
Subcellular localization of Type VI secretion system assembly in response to cell–cell contact
Bacteria require a number of systems, including the type VI secretion system (T6SS), for
interbacterial competition and pathogenesis. The T6SS is a large nanomachine that can …
interbacterial competition and pathogenesis. The T6SS is a large nanomachine that can …
Atomic structures of an entire contractile injection system in both the extended and contracted states
Contractile injection systems are sophisticated multiprotein nanomachines that puncture
target cell membranes. Although the number of atomic-resolution insights into contractile …
target cell membranes. Although the number of atomic-resolution insights into contractile …
Uncovering the Secretion Systems of Acinetobacter baumannii: Structures and Functions in Pathogenicity and Antibiotic Resistance
P Li, S Zhang, J Wang, MM Al-Shamiri, B Han, Y Chen… - Antibiotics, 2023 - mdpi.com
Infections led by Acinetobacter baumannii strains are of great concern in healthcare
environments due to the strong ability of the bacteria to spread through different apparatuses …
environments due to the strong ability of the bacteria to spread through different apparatuses …
Defending against the type six secretion system: beyond immunity genes
The bacterial type six secretion system (T6SS) delivers toxic effector proteins into
neighboring cells, but bacteria must protect themselves against their own T6SS. Immunity …
neighboring cells, but bacteria must protect themselves against their own T6SS. Immunity …
Immunity proteins of dual nuclease T6SS effectors function as transcriptional repressors
Bacteria utilize type VI secretion system (T6SS) to deliver antibacterial toxins to target co‐
habiting bacteria. Here, we report that Burkholderia gladioli strain NGJ1 deploys certain …
habiting bacteria. Here, we report that Burkholderia gladioli strain NGJ1 deploys certain …