Liposomes and polymersomes: a comparative review towards cell mimicking

E Rideau, R Dimova, P Schwille, FR Wurm… - Chemical society …, 2018 - pubs.rsc.org
Cells are integral to all forms of life due to their compartmentalization by the plasma
membrane. However, living organisms are immensely complex. Thus there is a need for …

Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Stimuli-responsive polymersomes for biomedical applications

X Hu, Y Zhang, Z **e, X **g, A Bellotti, Z Gu - Biomacromolecules, 2017 - ACS Publications
Polymersomes, the structural analogues of liposomes, are hollow structures enclosed by a
bilayer membrane made from amphiphilic copolymers. Polymersomes have been proposed …

Polymer prodrug-based nanoreactors activated by tumor acidity for orchestrated oxidation/chemotherapy

J Li, Y Li, Y Wang, W Ke, W Chen, W Wang, Z Ge - Nano letters, 2017 - ACS Publications
Therapeutic nanoreactors have been proposed to treat cancers through in situ
transformation of low-toxicity prodrugs into toxic therapeutics in the body. However, the in …

Hierarchical self-assembly of a copolymer-stabilized coacervate protocell

AF Mason, BC Buddingh', DS Williams… - Journal of the …, 2017 - ACS Publications
Complex coacervate microdroplets are finding increased utility in synthetic cell applications
due to their cytomimetic properties. However, their intrinsic membrane-free nature results in …

Therapeutic vesicular nanoreactors with tumor‐specific activation and self‐destruction for synergistic tumor ablation

J Li, A Dirisala, Z Ge, Y Wang, W Yin, W Ke… - Angewandte …, 2017 - Wiley Online Library
Polymeric nanoreactors (NRs) have distinct advantages to improve chemical reaction
efficiency, but the in vivo applications are limited by lack of tissue‐specificity. Herein, novel …

Peptide-guided resiquimod-loaded lignin nanoparticles convert tumor-associated macrophages from M2 to M1 phenotype for enhanced chemotherapy

P Figueiredo, A Lepland, P Scodeller, F Fontana… - Acta biomaterialia, 2021 - Elsevier
Nanomedicines represent innovative and promising alternative technologies to improve the
therapeutic effects of different drugs for cancer ablation. Targeting M2-like tumor-associated …

Self‐boosting catalytic nanoreactors integrated with triggerable crosslinking membrane networks for initiation of immunogenic cell death by pyroptosis

J Li, Y Anraku, K Kataoka - Angewandte Chemie, 2020 - Wiley Online Library
Synthetic polymer vesicles spur novel strategies for producing intelligent nanodevices with
precise and specific functions. Engineering vesicular nanodevices with tunable permeability …

Microfluidics for production of particles: mechanism, methodology, and applications

Z Liu, F Fontana, A Python, JT Hirvonen, HA Santos - Small, 2020 - Wiley Online Library
In the past two decades, microfluidics‐based particle production is widely applied for
multiple biological usages. Compared to conventional bulk methods, microfluidic‐assisted …

Tuning the Organ Tropism of Polymersome for Spleen‐Selective Nanovaccine Delivery to Boost Cancer Immunotherapy

W Gu, J An, Y Li, Y Yang, S Wang, H Shan… - Advanced …, 2023 - Wiley Online Library
The past few decades have witnessed explosive development in drug delivery systems.
However, in vivo delivery suffers from non‐specific distribution in non‐targeted organs or …