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Liposomes and polymersomes: a comparative review towards cell mimicking
Cells are integral to all forms of life due to their compartmentalization by the plasma
membrane. However, living organisms are immensely complex. Thus there is a need for …
membrane. However, living organisms are immensely complex. Thus there is a need for …
Polymersome-based protein drug delivery–quo vadis?
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …
approaches and represent one of the fastest growing families of drugs. While many of these …
Stimuli-responsive polymersomes for biomedical applications
Polymersomes, the structural analogues of liposomes, are hollow structures enclosed by a
bilayer membrane made from amphiphilic copolymers. Polymersomes have been proposed …
bilayer membrane made from amphiphilic copolymers. Polymersomes have been proposed …
Polymer prodrug-based nanoreactors activated by tumor acidity for orchestrated oxidation/chemotherapy
Therapeutic nanoreactors have been proposed to treat cancers through in situ
transformation of low-toxicity prodrugs into toxic therapeutics in the body. However, the in …
transformation of low-toxicity prodrugs into toxic therapeutics in the body. However, the in …
Hierarchical self-assembly of a copolymer-stabilized coacervate protocell
Complex coacervate microdroplets are finding increased utility in synthetic cell applications
due to their cytomimetic properties. However, their intrinsic membrane-free nature results in …
due to their cytomimetic properties. However, their intrinsic membrane-free nature results in …
Therapeutic vesicular nanoreactors with tumor‐specific activation and self‐destruction for synergistic tumor ablation
Polymeric nanoreactors (NRs) have distinct advantages to improve chemical reaction
efficiency, but the in vivo applications are limited by lack of tissue‐specificity. Herein, novel …
efficiency, but the in vivo applications are limited by lack of tissue‐specificity. Herein, novel …
Peptide-guided resiquimod-loaded lignin nanoparticles convert tumor-associated macrophages from M2 to M1 phenotype for enhanced chemotherapy
Nanomedicines represent innovative and promising alternative technologies to improve the
therapeutic effects of different drugs for cancer ablation. Targeting M2-like tumor-associated …
therapeutic effects of different drugs for cancer ablation. Targeting M2-like tumor-associated …
Self‐boosting catalytic nanoreactors integrated with triggerable crosslinking membrane networks for initiation of immunogenic cell death by pyroptosis
Synthetic polymer vesicles spur novel strategies for producing intelligent nanodevices with
precise and specific functions. Engineering vesicular nanodevices with tunable permeability …
precise and specific functions. Engineering vesicular nanodevices with tunable permeability …
Microfluidics for production of particles: mechanism, methodology, and applications
In the past two decades, microfluidics‐based particle production is widely applied for
multiple biological usages. Compared to conventional bulk methods, microfluidic‐assisted …
multiple biological usages. Compared to conventional bulk methods, microfluidic‐assisted …
Tuning the Organ Tropism of Polymersome for Spleen‐Selective Nanovaccine Delivery to Boost Cancer Immunotherapy
W Gu, J An, Y Li, Y Yang, S Wang, H Shan… - Advanced …, 2023 - Wiley Online Library
The past few decades have witnessed explosive development in drug delivery systems.
However, in vivo delivery suffers from non‐specific distribution in non‐targeted organs or …
However, in vivo delivery suffers from non‐specific distribution in non‐targeted organs or …