Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Copper-induced cell death, also known as cuproptosis, is distinct from other types of cell
death such as apoptosis, necrosis, and ferroptosis. It can trigger the accumulation of lethal …

Despite improvements in outcomes for children with B-and T-cell acute lymphoblastic
leukemia (B-ALL and T-ALL), patients with resistant or relapsed disease fare poorly …

Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents.
LncRNAs have recently gained widespread attention and have been shown to have crucial …

The epigenetic repressor BMI1 plays an integral role in promoting the self‐renewal and
proliferation of many adult stem cell populations, and also tumor types, primarily through …

Background Leukemia, a cancer impacting blood-forming tissues such as bone marrow and
the lymphatic system, presents in various forms, affecting children and adults differently. The …

Colorectal carcinoma (CRC) is the third most common malignant tumor in the world. In
recent years, the morbidity and mortality of CRC have increased in the world due to …

Future progress in the treatment of multiple myeloma (MM) requires both the
characterisation of key drivers of the disease and novel, innovative approaches to tackle …

Acute B-cell lymphoblastic leukemia (B-ALL) results from oligo-clonal evolution of B-cell
progenitors endowed with initiating and propagating leukemia properties. The activation of …

Gastric cancer remains the third leading cause of cancer-associated mortality worldwide.
The identification of prognostic indicators that are associated with clinical characteristics is …