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Polymeric nanocapsules: A review on design and production methods for pharmaceutical purpose
Polymeric nanocapsules have extensive application potential in medical, biological, and
pharmaceutical fields, and, therefore, much research has been dedicated to their production …
pharmaceutical fields, and, therefore, much research has been dedicated to their production …
Colloidal stability and degradability of silica nanoparticles in biological fluids: A review
A da Cruz Schneid, LJC Albuquerque… - Journal of Sol-Gel …, 2022 - Springer
This review shows the most common and promising strategies to generate colloidally stable
silica nanoparticles (NPs) in simulated biological fluids and sheds light on the latest …
silica nanoparticles (NPs) in simulated biological fluids and sheds light on the latest …
Brush conformation of polyethylene glycol determines the stealth effect of nanocarriers in the low protein adsorption regime
For nanocarriers with low protein affinity, we show that the interaction of nanocarriers with
cells is mainly affected by the density, the molecular weight, and the conformation of …
cells is mainly affected by the density, the molecular weight, and the conformation of …
Circulating immunotherapy strategy based on pyroptosis and STING pathway: Mn-loaded paclitaxel prodrug nanoplatform against tumor progression and metastasis
B Wang, T Wang, T Jiang, S Li, L Zhang, X Zhao… - Biomaterials, 2024 - Elsevier
Immunotherapy has emerged as a promising strategy against tumors. However, its efficacy
is limited by low immunogenicity, poor antigen presentation, and inadequate lymphocyte …
is limited by low immunogenicity, poor antigen presentation, and inadequate lymphocyte …
Anti-PEG antibodies enriched in the protein corona of PEGylated nanocarriers impact the cell uptake
MFS Deuker, V Mailänder, S Morsbach… - Nanoscale …, 2023 - pubs.rsc.org
Poly (ethylene glycol)(PEG) is the gold standard used to reduce unspecific protein
adsorption and prolong nanocarrier circulation time. However, this stealth effect could be …
adsorption and prolong nanocarrier circulation time. However, this stealth effect could be …
In situ characterization techniques of protein corona around nanomaterials
Nanoparticles (NPs) inevitably interact with proteins upon exposure to biological fluids,
leading to the formation of an adsorption layer known as the “protein corona”. This corona …
leading to the formation of an adsorption layer known as the “protein corona”. This corona …
Synthetic silica nano‐organelles for regulation of cascade reactions in multi‐compartmentalized systems
In eukaryotic cells, enzymes are compartmentalized into specific organelles so that different
reactions and processes can be performed efficiently and with a high degree of control. In …
reactions and processes can be performed efficiently and with a high degree of control. In …
Ultrasmall nanocapsules obtained by controlling Ostwald ripening
We describe here a method to synthesize ultrasmall nanocapsules with a diameter of 6 nm,
exhibiting a well‐defined core–shell morphology. Remarkably, the nanocapules are …
exhibiting a well‐defined core–shell morphology. Remarkably, the nanocapules are …
Temperature, concentration, and surface modification influence the cellular uptake and the protein corona of polystyrene nanoparticles
J Oberländer, C Champanhac, R da Costa Marques… - Acta Biomaterialia, 2022 - Elsevier
The composition of the protein corona varies depending on several parameters and
influences the cellular fate of the nanocarriers. Here, we investigated the influence of three …
influences the cellular fate of the nanocarriers. Here, we investigated the influence of three …
Current status of glucocorticoid usage in solid organ transplantation
S Dashti-Khavidaki, R Saidi… - World journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Glucocorticoids (GCs) have been the mainstay of immunosuppressive therapy in solid organ
transplantation (SOT) for decades, due to their potent effects on innate immunity and tissue …
transplantation (SOT) for decades, due to their potent effects on innate immunity and tissue …